Agent Name

Dicapthon

CAS Number

2463-84-5

Formula

C8-H9-Cl-N-O5-P-S

Major Category

Pesticides

Synonyms

2-Chloro-4-nitrophenyl dimethyl phosphorothioate; AC 4124; ACC 4124; American Cyanamid 4,124; BAY 14981; Bayer 22/190; Captec; Chlorthion; Dicaptan; Dicapthion; Dicapton; Dimethyl 2-chloronitrophenyl thiophosphate; ENT 17,035; Experimental Insecticide 4124; Insecticide ACC 4124; Isochloorthion; Isochloorthion [Dutch]; Isochlorothion; Isochlorthion; Isomeric chlorthion; Isomeric clorthio; O,O-Dimethyl O-(2-chloro-4-nitrophenyl)phosphorothioate; O,O-Dimethyl O-2-chloro-4-nitrophenyl phosphorothioate; O,O-Dimethyl-O-(2-chloro-4-nitrophenyl)thionophosphate; O-(2-Chloro-4-nitrophenyl) O,O-dimethyl phosphorothioate; O-(2-Chloro-4-nitrophenyl) O,O-dimethylphosphorothioate; O-(2-Chloor-4-nitro-fenyl)-O,O-dimethylmonothiofosfaat [Dutch]; O-(2-Chlor-4-nitro-phenyl)-O,O-dimethyl-monothiophosphat [German]; O-(2-Cloro-4-nitro-fenil)-O,O-dimetil-monotiofosfato [Italian]; OMS-214; Phenol, 2-chloro-4-nitro-, O-ester with O,O-dimethyl phosphorothioate; Phosnichlor; Phosnichlor [ISO]; Phosphorothioic acid O-(2-chloro-4-nitrophenyl) O,O-dimethyl ester; Thiophosphate de O,O-dimethyle et de O-2-chloro-4-nitrophenyle [French]; p-Nitro-o-chlorophenyl dimethyl thionophosphate; [ChemIDplus]

Category

Organophosphate Insecticides

Description

White solid; [Hawley]

Sources/Uses

Used as insecticide and acaricide for agricultural, household, and public health pest control; Also used for tick control in domestic animals; [HSDB]

Comments

A cholinesterase inhibitor; [Hawley] The only adverse effect noted in one year feeding study with rats (250 ppm highest dose group) was retarded growth; [HSDB] The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline. [TLVs and BEIs]

Restricted

Cancelled--no longer registered as a pesticide for use in the US; [HSDB]

Exposure Assessment
BEI

Acetylcholinesterase activity in red blood cells = 70% of individual's baseline; Butylcholinesterase activity in serum or plasma = 60% of individual's baseline; Sample at end of shift; [TLVs and BEIs]

Vapor Pressure

3.6E-6 mm Hg

Adverse Effects
Other Poison

Organophosphate

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: