Agent Name

Dichloroethane, all isomers

CAS Number

1300-21-6

Formula

C2-H4-Cl2

Major Category

Solvents

Synonyms

Ethane, dichloro-; [ChemIDplus] UN2362

Category

Chlorinated Aliphatics

Sources/Uses

Used to make vinyl chloride monomer and 1,1,1-trichloroethane; [HSDB]

Comments

The halogenated solvents are CNS depressants; A 14 year old boy developed fatal hepatorenal syndrome after ingesting about 50 ml of dichloroethane; [Sullivan, p. 739-40] See "1,1-Dichlroethane" and "Ethylene dichloride."

Exposure Assessment
Lethal Concentration

LCLo (mice) = 10,000 mg/m3

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "1,1-Dichloroethane."

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Hepatotoxin

Hepatotoxin, Secondary

Nephrotoxin

Yes

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: