Agent Name

Ethyl bromide

Alternative Name

Bromoethane

CAS Number

74-96-4

Formula

C2-H5-Br

Major Category

Solvents

Synonyms

Bromic ether; Bromoethane; Bromure d'ethyle; Ethane, bromo-; Ethyl bromide; Etylu bromek [Polish]; Halon 2001; Hydrobromic ether; Monobromoethane; [ChemIDplus] UN1891

Category

Brominated Solvents

Description

Colorless to yellow liquid with an ether-like odor; Note: A gas above 101 degrees F; [NIOSH]

Sources/Uses

Used in organic synthesis and as a solvent for chemicals and pharmaceuticals; Used in the past as a refrigerant and an anesthetic; [ACGIH]

Comments

Anesthesia and liver toxicity occur in animal inhalation studies; [ACGIH] A skin, eye, and respiratory tract irritant; Inhalation of high concentrations can cause CNS depression; [ICSC]

Exposure Assessment
Skin Designation (ACGIH)

Yes

TLV (ACGIH)

5 ppm

PEL (OSHA)

200 ppm

IDLH (NIOSH)

2000 ppm

Excerpts from Documentation for IDLHs

Concentrations of 12,000 ppm caused immediate eye irritation in volunteers and 5 minutes at 6,500 ppm resulted in eye irritation, headache, and vertigo [Sayers and Yant 1929]. Workers exposed intermittently to concentrations up to 1,500 ppm complained of no systematic symptoms over a period of several years [Watrous 1947].

Vapor Pressure

467 mm Hg

Odor Threshold Low

3.1 ppm

Lethal Concentration

LC50 (rat) = 26,980 ppm/1H

Explanatory Notes

Odor threshold from CHEMINFO; Flash point = -20 deg C;

Flammability (NFPA)

3: May ignite at ambient temperature

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Hepatotoxin

Hepatotoxin, Secondary

IARC Carcinogen

Not Classifiable

ACGIH Carcinogen

Confirmed Animal

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: