Agent Name

Ethyl butyl ketone

Alternative Name

3-Heptanone

CAS Number

106-35-4

Formula

C7-H14-O

Major Category

Solvents

Synonyms

3-Heptanone; Aethylbutylketon [German]; Butyl ethyl ketone; Eptan-3-one [Italian]; Ethyl butyl ketone; Ethyl n-butyl ketone; Ethylbutylcetone [French]; Ethylbutylketon [Dutch]; Etilbutilchetone [Italian]; Heptan-3-on [Dutch, German]; Heptan-3-one; n-Butyl ethyl ketone; [ChemIDplus] UN1224

Category

Ketones (<C12)

Description

Colorless liquid with a powerful, fruity odor; [NIOSH]

Sources/Uses

Used as a fragrance and a solvent for resins and coatings; it occurs naturally in breads. [ACGIH]

Comments

Inhalation of high concentrations can cause CNS depression; A skin, eye, and respiratory tract irritant; [ICSC]

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TLV (ACGIH)

50 ppm

STEL (ACGIH)

75 ppm

PEL (OSHA)

50 ppm

MAK

10 ppm

IDLH (NIOSH)

1000 ppm

Excerpts from Documentation for IDLHs

Basis for original (SCP) IDLH: The chosen IDLH is based on the statements by Patty [1963] and Deichmann and Gerarde [1969] that 0 rats died following a 4hour exposure to 2,000 ppm, but 6 of 6 rats died following a 4hour exposure to 4,000 ppm [Smyth et al. 1949]. . . . Human data: None relevant for use in determining the revised IDLH.

Vapor Pressure

2.6 mm Hg

Odor Threshold Low

0.1 ppm

Odor Threshold High

10 ppm

Lethal Concentration

LCLo (rat) = 2,000 ppm/4H

Explanatory Notes

Odor threshold from "Quick Guide: The Electronic NIOSH Pocket Guide to Chemical Hazards"; Flash point = 46 deg C;

Flammability (NFPA)

2: High ambient temperature required

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: