Agent Name

Diethylene glycol monomethyl ether

Alternative Name

DEGME

CAS Number

111-77-3

Formula

C5-H12-O3

Major Category

Solvents

Synonyms

2-(2-Methoxyethoxy)ethanol; 3,6-Dioxa-1-heptanol; DEGME; Diethylene glycol methyl ether; Diethyleneglycol monomethyl ether; Diglycol monomethyl ether; Dowanol 16; Dowanol DM; EGME, di-; Ektasolve DM; Ethanol, 2,2'-oxybis-, monomethyl ether; Ethanol, 2-(2-methoxyethoxy)-; Ethylene diglycol monomethyl ether; Jeffersol DM; MECB; Methoxydiglycol; Methyl carbitol; Methyl digol; Methyl dioxitol; Methyl karbitol [Czech]; Poly-Solv DM; beta-Methoxy-beta'-hydroxydiethyl ether; [ChemIDplus]

Category

Glycol Ethers (E Series)

Description

Colorless liquid; [Hawley] Hygroscopic; [HSDB]

Sources/Uses

Used as a solvent for wood stains, lacquers, inks, textile dye pastes, paints, waxes, dyes, and nitrocellulose resins; Also used in brake fluid, aviation fuel anti-icing additive, and inert ingredient in pesticides; [HSDB] Used as an intermediate; [Hawley] Not produced commercially in the EU; [Glycol Ethers Online]

Comments

Defats the skin; Can be absorbed through the skin; "Animal tests show that this substance possibly causes toxicity to human reproduction or development." [ICSC] Labeled as "May impair fertility" and "May cause harm to the unborn child" by EU regulations; [Glycol Ethers Online] Readily oxidizes in air forming unstable peroxides that can spontaneously explode; May cause eye irritation; [CAMEO] An irritant; [MSDSonline] See "GLYCOL ETHERS."

Exposure Assessment
Vapor Pressure

0.25 mm Hg

Lethal Concentration

LC (rat) > 2,000 mg/m3/1h

Flammability (NFPA)

2: High ambient temperature required

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Hepatotoxin

Hepatotoxin, Secondary

Nephrotoxin

Yes

Reproductive Toxin

Yes

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: