Agent Name

Diethylene glycol monomethyl ether

Alternative Name

DEGME

CAS Number

111-77-3

Formula

C5-H12-O3

Major Category

Solvents

Synonyms

2-(2-Methoxyethoxy)ethanol; 3,6-Dioxa-1-heptanol; DEGME; Diethylene glycol methyl ether; Diethyleneglycol monomethyl ether; Diglycol monomethyl ether; Dowanol 16; Dowanol DM; EGME, di-; Ektasolve DM; Ethanol, 2,2'-oxybis-, monomethyl ether; Ethanol, 2-(2-methoxyethoxy)-; Ethylene diglycol monomethyl ether; Jeffersol DM; MECB; Methoxydiglycol; Methyl carbitol; Methyl digol; Methyl dioxitol; Methyl karbitol [Czech]; Poly-Solv DM; beta-Methoxy-beta'-hydroxydiethyl ether; [ChemIDplus]

Category

Glycol Ethers (E Series)

Description

Colorless liquid; [Hawley] Hygroscopic; [HSDB]

Sources/Uses

Used as a solvent for wood stains, lacquers, inks, textile dye pastes, paints, waxes, dyes, and nitrocellulose resins; Also used in brake fluid, aviation fuel anti-icing additive, and inert ingredient in pesticides; [HSDB] Used as an intermediate; [Hawley] Not produced commercially in the EU; [Glycol Ethers Online]

Comments

Defats the skin; Can be absorbed through the skin; "Animal tests show that this substance possibly causes toxicity to human reproduction or development." [ICSC] Labeled as "May impair fertility" and "May cause harm to the unborn child" by EU regulations; [Glycol Ethers Online] Readily oxidizes in air forming unstable peroxides that can spontaneously explode; May cause eye irritation; [CAMEO] An irritant; [MSDSonline] See "GLYCOL ETHERS."

Exposure Assessment
Vapor Pressure

0.25 mm Hg

Lethal Concentration

LC (rat) > 2,000 mg/m3/1h

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Hepatotoxin

Hepatotoxin, Secondary

Nephrotoxin

Yes

Reproductive Toxin

Yes

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: