Agent Name

Difenacoum

CAS Number

56073-07-5

Formula

C31-H24-O3

Major Category

Pesticides

Synonyms

2H-1-Benzopyran-2-one, 3-(3-(1,1'-biphenyl)-4-yl-1,2,3,4-tetrahydro-1-naphthalenyl)-4-hydroxy-; 3-(3-(1,1'-Biphenyl)-4-yl-1,2,3,4-tetrahydro-1-naphthalenyl)-4-hydroxy-2H-1-benzopyran-2-one; 3-(3-Biphenyl-4-yl-1,2,3,4-tetrahydro-1-naphthyl)-4-hydroxycoumarin; Difenakum [Czech]; Diphenacoum; Neosorexa; Neosorexa PP580; Ratak; WBA 8107; [ChemIDplus] UN3027

Category

Rodenticides, Anticoagulant

Description

Off-white odorless solid; [HSDB]

Sources/Uses

Used as second generation anticoagulant rodenticide; [Merck Index] Registered in 2007 for use in the US in and around buildings and in transport vehicles; Has been registered in European countries since the 1970's; [Reference #1]

Comments

A vitamin K antagonist--causes clotting factor disruption and bleeding tendency; Two patients had abnormal vitamin K1 metabolism for more than 18 months after exposure, although prothrombin time and vitamin K-dependent clotting factors were normal; No unscheduled DNA synthesis induced in rat hepatocytes; [HSDB] See "Warfarin."

Reference Link

EPA Pesticide Chemical Search

Exposure Assessment
Vapor Pressure

1.2E-6 mm Hg

Lethal Concentration

LC50 (rat) => 3.64 mg/m3

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Coumarin derivative pesticide, solid, toxic."

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Processes

Industrial Processes with risk of exposure: