Agent Name

2,4-Diaminophenol dihydrochloride

CAS Number

137-09-7

Formula

C6-H8-N2-O.2Cl-H

Major Category

Nitrogen Compounds

Synonyms

2,4-Diaminophenol HCl; 2,4-Diaminophenol hydrochloride; Acrol; Amidol; Diamidophenol hydrochloride; Dianol; Phenol, 2,4-diamino-, dihydrochloride; [ChemIDplus]

Category

Amino Phenols

Description

Grayish-white solid; [HSDB] Slightly gray crystalline solid; [MSDSonline]

Sources/Uses

Used as photographic developer, analytical reagent, and in fur and hair dyeing; [HSDB]

Comments

Limited evidence of mutagenicity and carcinogenicity in male mice; No evidence of carcinogenicity in female mice or male and female rats; Emergency treatment: "Paraphenylenediamine"; In sensitized individuals, paraphenylenediamine may cause allergic contact dermatitis following application as a hair dye and asthma following inhalation; Following ingestion, can cause angioneurotic edema, methemoglobinemia, acute tubular necrosis, and hepatotoxicity; An adult died after ingestion of 3 grams of p-phenylenediamine; Another adult who ingested 1800 mg developed angioneurotic edema and acute renal failure; [HSDB] May cause irritation and allergic reactions; [CAMEO] Causes changes in liver and bladder weight, erythrocyte count, and levels of transaminases in high-dose feeding studies of mice; [RTECS] See "p-Phenylenediamine."

Adverse Effects
Skin Sensitizer

Yes

Hepatotoxin

Hepatotoxin, Secondary

Methemoglobinemia

Methemoglobinemia, Secondary

Links to Other NLM Databases
Health Studies

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Chemical Information

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