Agent Name

2-Nitro-1,4-benzenediamine dihydrochloride

CAS Number

18266-52-9

Formula

C6-H7-N3-O2.2Cl-H

Major Category

Nitrogen Compounds

Synonyms

1,4-Benzenediamine, 2-nitro-, dihydrochloride; p-Phenylenediamine, 2-nitro-, dihydrochloride; 2-Nitrobenzene-1,4-diamine dihydrochloride; [ChemIDplus]

Category

Other Aromatics (Nitrogen)

Comments

May potentially induce methemoglobinemia; Emergency treatment: "Paraphenylenediamine"; In sensitized individuals, p-phenylenediamine may cause allergic contact dermatitis following application as a hair dye and asthma following inhalation; Following ingestion, can cause angioneurotic edema, methemoglobinemia, acute tubular necrosis, and hepatotoxicity; An adult died after ingestion of 3 grams of p-phenylenediamine; Another adult who ingested 1800 mg developed angioneurotic edema and acute renal failure; [HSDB] See "p-Phenylenediamine."

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

Methemoglobinemia

Methemoglobinemia, Secondary

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