Agent Name

3,3'-Dichlorobenzidine dihydrochloride

CAS Number

612-83-9

Formula

C12-H10-Cl2-N2.2Cl-H

Major Category

Nitrogen Compounds

Synonyms

(1,1'-Biphenyl)-4,4'-diamine, 3,3'-dichloro-, dihydrochloride; 3,3'-Dichlorobenzidine hydrochloride; Benzidine, 3,3'-dichloro-, dihydrochloride; [ChemIDplus] UN3077

Category

Benzidine and Derivatives

Description

White to light-gray solid; [HSDB] Light tan solid; [CAMEO]

Sources/Uses

Used to make azo dyes and pigments (Benzidine Yellow); Also used as a curing agent for isocyanate polymers and solid urethane plastics; [Merck Index]

Comments

A mutagen and tumorigen; [RTECS] Overexposure may cause skin sensitization, caustic burns, and hematuria; [Merck Index] Emergency treatment: Irritants; Severely irritating to eyes; [HSDB] May cause skin sensitization; [CAMEO] May cause skin sensitization; Severely restricted for industrial use in the EU; [eChemPortal: ESIS] May cause irritation; May cause skin sensitization; Targets the bladder and liver; [MSDSonline] See "3,3'-Dichlorobenzidine."

Exposure Assessment
Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Environmentally hazardous substances, solid, n.o.s."

Adverse Effects
Skin Sensitizer

Yes

Hepatotoxin

Hepatotoxin, Secondary

NTP Carcinogen

Anticipated Human Carcinogen

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: