Agent Name

Diisopropanolamine

CAS Number

110-97-4

Formula

C6-H15-N-O2

Major Category

Nitrogen Compounds

Synonyms

1,1'-Iminobis-2-propanol; 1,1'-Iminodi-2-propanol; Bis(2-hydroxypropyl)amine; Bis(2-propanol)amine; DIPA; DIPA (alcohol); Di-2-propanolamine; Diisopropanolamine; Dipropyl-2,2'-dihydroxy-amine; N,N-Bis(2-hydroxypropyl)amine; 1,1'-Iminodipropan-2-ol; 2-Propanol, 1,1'-iminobis-; 2-Propanol, 1,1'-iminodi-; [ChemIDplus] UN3259

Category

Amines, Aliphatic

Description

White hygroscopic solid; Yellows upon light and air exposure; mp = 42 deg C; [ICSC] May also be in the form of colorless liquid; Odor of dead fish; [CAMEO] White solid; mp = 43-47 deg C; [MSDSonline]

Sources/Uses

Used as chemical intermediate, emulsifying agent (polishes, textile specialties, leather compounds, insecticides, cold wave permanent hair solutions, and water paints), antimicrobial agent in cutting fluids, and for removal of hydrogen sulfide and carbon dioxide from natural and industrial gases; Also used in adhesives, paper and paperboard, coatings, food packaging, and in prescription drugs; [HSDB]

Comments

A skin, eye, and nasal irritant; No allergic or photoallergic dermatitis observed in 25 volunteers; Weak skin sensitization reported from occupational exposure; Causes burns to rabbit eyes; Causes severe necrosis to rabbit skin; [HSDB] An eye irritant; [eChemPortal: ESIS] Hypothermia, diarrhea, uncoordinated movements, and seizures observed in lethal-dose animal studies; [IUCLID] No effects on fetal development when administered by gavage to pregnant rats; No data on effects to human pregnancy; [REPROTOX] A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; Can be absorbed through skin; Inhalation may cause pulmonary edema; [MSDSonline]

Exposure Assessment
Vapor Pressure

0.000125 mm Hg

Lethal Concentration

LC50 (rat) > 795 mg/m3

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Amines, solid, corrosive, n.o.s."

Flammability (NFPA)

1: Must be preheated

Adverse Effects
Toxic Pneumonitis

Yes

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Processes

Industrial Processes with risk of exposure: