Agent Name

Fluorotrichloromethane

Alternative Name

Trichlorofluoromethane

CAS Number

75-69-4

Formula

C-Cl3-F

Major Category

Solvents

Synonyms

Trichlorofluoromethane; Algofrene type 1; Arcton 11; Arcton 9; CFC 11; Chladone 11; Daiflon 11; Daiflon S 1; Dymel 11; Electro-CF 11; Eskimon 11; F 11; F 11 (halocarbon); F 11B; F-11; FC 11; FC 11 (halocarbon); FKW 11; Fluon 11; Fluorocarbon 11; Fluorocarbon No. 11; Fluorochloroform; Fluorotrichloromethane; Fluorotrojchlorometan [Polish]; Freon 11; Freon 11A; Freon 11B; Freon HE; Freon MF; Frigen 11; Frigen 11A; Frigen S 11; Genetron 11; Genetron 11SBA; Halocarbon 11; Halon 11; Isceon 131; Isotron 11; Kaltron 11; Khladon 11; Ledon 11; Methane, fluorotrichloro-; Monofluorotrichloromethane; Propellant 11; R 11; R 11 (refrigerant); Refrigerant 11; Refrigerant R 11; Trichlorofluorocarbon; Trichlorofluoromethane; Trichloromethyl fluoride; Trichloromonofluoromethane; Ucon flurocarbon 11; Ucon refrigerant 11; [ChemIDplus] UN2810

Category

Chlorofluorocarbons

Description

Colorless to water-white, nearly odorless liquid or gas (above 75 degrees F); [NIOSH]

Sources/Uses

CFC-11 has been used as a blowing agent, a refrigerant, and an aerosol propellant. [ACGIH] Used in photography (film cleaner); [www.ci.tucson.az.us/arthazards/medium.html]

Comments

Fluorotrichloromethane is in the list of "Some volatile substances which may be abused by inhalation" published on the web site of the U.N. International Drug Control Programme, indicating its potential to cause narcosis in workers. [Reference #1] Evaporating liquid can cause frostbite; Inhalation of high concentrations can cause CNS depression and cardiac arrhythmias; [ICSC]

Restricted

See CHLOROFLUOROCARBONS

Reference Link

Volatile Substance Abuse

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

Ceiling (ACGIH)

1000 ppm

PEL (OSHA)

1000 ppm

MAK

1000 ppm

IDLH (NIOSH)

2000 ppm

Excerpts from Documentation for IDLHs

Evidence of serious arrhythmia was noted in 1 of 12 conscious dogs exposed for 5 minutes to 5,000 ppm plus intravenous epinephrine [Reinhardt et al. 1971]. However, in another study, endogenous epinephrin was not sufficient to precipitate arrythmia in dogs exposed to 5,000 to 10,000 ppm [Reinhardt et al. 1971].

Vapor Pressure

803 mm Hg

Odor Threshold Low

200000 ppm

Lethal Concentration

LC50 (rat) = 130,000 ppm/15 min

Explanatory Notes

Odor threshold is 200,000 ppm (20% by volume). [CHEMINFO]

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

ACGIH Carcinogen

Not Classifiable

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: