Agent Name

Dinitrobenzene

CAS Number

25154-54-5

Formula

C6-H4-N2-O4

Major Category

Nitrogen Compounds

Synonyms

Benzene, dinitro-; DNB; Dinitrobenzenes; Dinitrobenzol; Dinitrobenzene, mixed; [ChemIDplus] UN3443; UN1597

Category

Nitros, Aromatic

Description

White to pale yellow solid; [ICSC]

Sources/Uses

Used to make other chemicals, in dyes, and as a camphor substitute in cellulose nitrate; [Hawley]

Comments

Emergency treatment: "Nitrobenzene"; Nitrobenzene causes skin irritation; It is toxic by all routes causing methemoglobinemia and liver injury; Estimated lethal dose in adults is 1-5 grams; [HSDB] An eye and respiratory tract irritant; Can be absorbed through skin; May induce methemoglobinemia and liver injury; May cause impairment of visual acuity; Reproductive toxin in animal testing; [ICSC] See "p-Dinitrobenzene."

Exposure Assessment
BEI

Methemoglobin in blood = 1.5% of hemoglobin during or at end of shift. [ACGIH]

Skin Designation (ACGIH)

Yes

TLV (ACGIH)

1 mg/m3

PEL (OSHA)

1 mg/m3

Vapor Pressure

0.00103 mm Hg

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Dinitrobenzenes, solid." See "2018 Notice of Intended Changes." [TLVs and BEIs]

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

Methemoglobinemia

Methemoglobinemia, Secondary

Links to Other NLM Databases
Health Studies

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