Agent Name

Dinitrobenzene

CAS Number

25154-54-5

Formula

C6-H4-N2-O4

Major Category

Nitrogen Compounds

Synonyms

Benzene, dinitro-; DNB; Dinitrobenzenes; Dinitrobenzol; Dinitrobenzene, mixed; [ChemIDplus] UN3443; UN1597

Category

Nitros, Aromatic

Description

White to pale yellow solid; [ICSC]

Sources/Uses

Used to make other chemicals, in dyes, and as a camphor substitute in cellulose nitrate; [Hawley]

Comments

Emergency treatment: "Nitrobenzene"; Nitrobenzene causes skin irritation; It is toxic by all routes causing methemoglobinemia and liver injury; Estimated lethal dose in adults is 1-5 grams; [HSDB] An eye and respiratory tract irritant; Can be absorbed through skin; May induce methemoglobinemia and liver injury; May cause impairment of visual acuity; Reproductive toxin in animal testing; [ICSC] See "p-Dinitrobenzene."

Exposure Assessment
BEI

Methemoglobin in blood = 1.5% of hemoglobin during or at end of shift. [ACGIH]

Skin Designation (ACGIH)

Yes

TLV (ACGIH)

1 mg/m3

PEL (OSHA)

1 mg/m3

Vapor Pressure

0.00103 mm Hg

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Dinitrobenzenes, solid."

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

Methemoglobinemia

Methemoglobinemia, Secondary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Other Information

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