Agent Name

sec-Hexyl acetate

CAS Number

108-84-9

Formula

C8-H16-O2

Major Category

Solvents

Synonyms

1,3-Dimethylbutyl acetate; 1,3-Dimethylbutyl ethanoate; 1,3-Dimethylbutylester kyseliny octove [Czech]; 2-Pentanol, 4-methyl-, acetate; 4-Methyl-2-amyl acetate; 4-Methyl-2-pentanol, acetate; 4-Methyl-2-pentyl acetate; Acetic acid, 1,3-dimethylbutyl ester; Methyl amyl acetate; Methylamyl acetate; Methylisoamyl acetate; Methylisobutylcarbinol acetate; Methylisobutylcarbinyl acetate; sek.Isohexylester kyseliny octove [Czech]; [ChemIDplus] UN1233

Category

Esters (<C12)

Description

Colorless liquid with a mild, pleasant, fruity odor; [NIOSH]

Sources/Uses

Used as a lacquer solvent and fragrance; [ACGIH]

Comments

Esters may induce narcosis in animals, but workers' exposures are limited by irritating effects. See appendix in: [Dick RB, et al. Chemicals in the workplace: incorporating human neurobehavioral testing into the regulatory process. Am J Ind Med. 1998 May;33(5):439-53.] A skin, eye, and respiratory tract irritant; Inhalation of high concentrations can cause CNS depression; [ICSC]

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TLV (ACGIH)

50 ppm

PEL (OSHA)

50 ppm

IDLH (NIOSH)

500 ppm

Excerpts from Documentation for IDLHs

Volunteers noted an unpleasant odor and irritation of the eyes and upper respiratory tract at 100 ppm [Silverman et al. 1946].

Vapor Pressure

4 mm Hg

Odor Threshold Low

0.39 ppm

Lethal Concentration

LCLo (rat) = 2,000 ppm/4H

Explanatory Notes

Odor threshold from AIHA; Flash point = 45 deg C;

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: