Agent Name

Erucic acid

CAS Number

112-86-7

Formula

C22-H42-O2

Major Category

Other Classes

Synonyms

13-cis-Docosenoic acid; Hystrene 2290; Z-13-Docosenoic acid; cis-13-Docosenoic acid; delta13-cis-Docosenoic acid; delta13:14-Docosenoic acid; (Z)-Docos-13-enoic acid; 13-Docosenoic acid, (13Z)-; 13-Docosenoic acid, (Z)-; [ChemIDplus]

Category

Organic Acids

Description

Solid; mp = 33.8 deg C; [Merck Index] Fine white crystals; [MSDSonline]

Sources/Uses

Isolated from the fats and oils of mustard seed, rapeseed, and crambe seed; [Hawley] Used as lubricant additive and chemical intermediate; [HSDB]

Comments

Caused asymptomatic thrombocytopenia in patients receiving Lorenzo's oil (erucic acid and oleic acid); Low platelet count reversed within 2-3 weeks of discontinuing erucic acid; Rabbits fed 40 cal% rapeseed oil versus 40 cal% sunflower oil for 84 weeks developed myocardial fibrosis, hepatic cirrhosis, and increased serum cholesterol; [HSDB] An irritant; Targets the liver and heart; [MSDSonline]

Exposure Assessment
Vapor Pressure

1.15E-6 mm Hg

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Processes

Industrial Processes with risk of exposure: