Agent Name

Hydrogen selenide

CAS Number

7783-07-5

Formula

H2-Se

Major Category

Toxic Gases & Vapors

Synonyms

Dihydrogen selenide; Electronic E-2; Hydrogen selenide (H2Se); Selane; Selenium anhydride; Selenium dihydride; Selenium hydride; [ChemIDplus] UN2202

Category

Hydrides

Description

Colorless gas with an odor resembling decayed horse radish. [Note: Shipped as a liquefied compressed gas.]; [NIOSH]

Sources/Uses

Used in semiconductor preparation and in organic synthesis; a product of the reaction of acids and inorganic selenides; [ACGIH]

Comments

Experimental animals show signs of respiratory irritation and die after 8 hour exposures of 1 mg/m3 (0.3 ppm). Pathological examination shows evidence of liver damage. Inhalation of hydrogen selenide by workers has caused eye, nose, and respiratory irritation. Pulmonary edema is a potential toxic effect. [ACGIH] Hydrogen selenide "is probably the only selenium compound that might pose a health concern in the workplace." [ATSDR ToxFAQs] Possible frostbite from contact with liquid; [NIOSH] A skin, eye, and respiratory tract irritant; May cause liver injury; May cause pulmonary edema; [ICSC] See "Selenium."

Reference Link

ATSDR - ToxFAQs - Selenium

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TIH

Yes

TLV (ACGIH)

0.05 ppm

PEL (OSHA)

0.05 ppm, as Se

MAK

0.006 ppm

IDLH (NIOSH)

1 ppm

Excerpts from Documentation for IDLHs

Human data: Although very toxic, no fatalities have been reported, possibly because hydrogen selenide is easily oxidized to red selenium on the surface of mucous membranes of the nose and throat [Friberg et al. 1979]. Concentrations of 1.5 ppm have been found to be intolerable due to eye and nasal irritation [Dudley and Miller 1941].

Odor Threshold Low

0.3 ppm

Lethal Concentration

LCLo (rat) = 20 mg/m3/1H

Explanatory Notes

Odor threshold from AIHA;

Reference Link

ICSC: Hydrogen selenide

Adverse Effects
Toxic Pneumonitis

Yes

Hepatotoxin

Hepatotoxin, Secondary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: