Agent Name

Ethylene glycol diacetate

Alternative Name

EGD

CAS Number

111-55-7

Formula

C6-H10-O4

Major Category

Other Classes

Synonyms

EGD; 1,2-Diacetoxyethane; 1,2-Ethanediol diacetate; Aptex Donor H-plus; Ethanediol diacetate; Ethylene diacetate; Ethylene diethanoate; Ethylene glycol, diacetate; Glycol diacetate; [ChemIDplus] UN1993

Category

Ethylene Glycols

Description

Colorless liquid; [Hawley]

Sources/Uses

Used as solvent for oils, explosives, cellulose esters, cellulose ethers, natural products, printing inks, perfume fixatives, resins, and lacquers; Also used as a non-discoloring plasticizer for ethyl and benzyl cellulose; [HSDB] Used mainly as a re-flow solvent in thermoplastic acrylic coatings and in foundries (slow-release source of acetic acid for making cores); Also used as an ink solvent; [Reference #1]

Comments

Its toxicity in animal experiments is thought to be due to metabolic conversion into ethylene glycol (EG); Animals poisoned with EGD have urinary oxalate crystals, an almost pathognomic sign of EG toxicosis; [Reference #1] A mild eye irritant; [HSDB]; Causes general anesthesia in oral lethal-dose studies; Other adverse effects in multiple dose tests were changes in the blood and liver; [RTECS] Caused kidney stone formation and kidney damage in high-dose feeding studies of animals; [CHEMINFO] A mild skin irritant; [MSDSonline] See "Ethylene glycol."

Reference Link

EPA ChAMP HPV: Ethylene glycol diacetate - 2002

Exposure Assessment
Vapor Pressure

0.07 mm Hg

Odor Threshold Low

0.09 ppm

Odor Threshold High

0.31 ppm

Explanatory Notes

Odor threshold low (absolute perception limit) and high (for both 50% and 100% recognition) from HSDB; The Guide in the Emergency Response Guidebook is for "Combustible liquid, n.o.s."

Flammability (NFPA)

2: High ambient temperature required

Adverse Effects
Neurotoxin

Other CNS Neurotoxin

Hepatotoxin

Hepatotoxin, Secondary

Nephrotoxin

Yes

Links to Other NLM Databases
Health Studies

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Toxicity Information

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Chemical Information

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