Agent Name

Iodoform

CAS Number

75-47-8

Formula

C-H-I3

Major Category

Other Uses

Synonyms

Carbon triiodide; Dezinfekt V; Jodoform [Czech]; Methane, triiodo-; Triiodomethane; Trijodmethane [Czech]; [ChemIDplus]

Category

Pharmaceuticals

Description

Yellow to greenish-yellow powder or crystalline solid with a pungent, disagreeable odor. [antiseptic for external use]; [NIOSH]

Sources/Uses

Used as a disinfectant and veterinary antiseptic; [Merck Index, #5033]

Comments

Cases of CNS depression, delirium, and hallucinations were reported when iodoform was used as a topical antiseptic and absorbed through the wound. It causes severe liver injury in animal experiments. [ACGIH]

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TLV (ACGIH)

0.6 ppm

Vapor Pressure

0.04 mm Hg

Odor Threshold Low

1.9E-5 ppm

Odor Threshold High

1.1 ppm

Lethal Concentration

LC50 (rat) = 165 ppm/7h

Explanatory Notes

Odor threshold from AIHA; See "2017 Notice of Intended Changes." [TLVs and BEIs]

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Processes

Industrial Processes with risk of exposure: