Agent Name

Ethyl isocyanate

CAS Number

109-90-0

Formula

C3-H5-N-O

Major Category

Toxic Gases & Vapors

Synonyms

Ethane, isocyanato-; Isocyanatoethane; Isocyanic acid, ethyl ester; [ChemIDplus] UN2481

Category

Monoisocyanates

Description

Liquid; [Hawley] Colorless liquid; [CAMEO]

Sources/Uses

Used as an intermediate for pharmaceuticals and pesticides; [Hawley]

Comments

An irritant that can cause acute inhalation injury; [HSDB] A strong irritant; [Hawley] Highly flammable; May react with water forming a corrosive liquid and carbon dioxide gas; May cause irritation; Inhalation may be fatal; [CAMEO] A lachrymator; A severe skin, eye, and respiratory tract irritant capable of causing severe injury and permanent damage; Inhalation may cause sufficient damage to lungs and respiratory system to cause death; Symptoms include convulsions, chemical bronchitis, pulmonary edema, and coma; A possible skin and respiratory sensitizer; [CHEMINFO] A dermal sensitizer; [ACGIH] A skin and eye irritant; May cause respiratory sensitization after prolonged contact; [eChemPortal: ERMA] A lachrymator; An irritant; May cause respiratory sensitization after prolonged contact; Effects in high-dose animal studies include convulsions and lacrimation; [MSDSonline] See "MONOISOCYANATES."

Exposure Assessment
Skin Designation (ACGIH)

Yes

TIH

Yes

TLV (ACGIH)

0.02 ppm

STEL (ACGIH)

0.06 ppm

Vapor Pressure

17.5 mm Hg

Lethal Concentration

LCLo (rat) = 240 mg/m3/6h

Adverse Effects
Skin Sensitizer

Yes

Lacrimator

Yes

Toxic Pneumonitis

Yes

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: