Agent Name

Iron pentacarbonyl

CAS Number

13463-40-6

Formula

C5-Fe-O5

Major Category

Toxic Gases & Vapors

Synonyms

Iron carbonyl; Pentacarbonyl iron; [NIOSH]

Category

Other Toxic Gases & Vapors

Description

Colorless to yellow to dark-red, oily liquid; [NIOSH] Ignites in air; Insoluble in water; [Sullivan, p. 979]

Sources/Uses

Used as an anti-knock agent in gasoline in Europe; may be generated when fine iron particles react with carbon monoxide; [ACGIH]

Comments

Acute inhalation studies of animals: lung irritation and pulmonary edema are prominent toxic effects. [ACGIH] Also can cause liver,kidney, and CNS injury; [CAMEO] Readily absorbed through the skin; Acute exposure can injure the lungs (pneumonitis), liver, and kidneys. Chronic exposure can cause iron overload and hemochromatosis. [Sullivan, p. 982] See "ORGANOMETALS."

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TIH

Yes

Bioaccumulates

Yes

TLV (ACGIH)

0.1 ppm

STEL (ACGIH)

0.2 ppm

MAK

0.1 ppm

Vapor Pressure

21 mm Hg

Explanatory Notes

Flash point = 5 deg F; [CAMEO]

Reference Link

ICSC: Iron pentacarbonyl

Adverse Effects
Toxic Pneumonitis

Yes

Neurotoxin

Other CNS Neurotoxin

Hepatotoxin

Hepatotoxin, Secondary

Nephrotoxin

Yes

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: