Agent Name

Isoamyl alcohol

CAS Number

123-51-3

Formula

C5-H12-O

Major Category

Solvents

Synonyms

1-Butanol, 3-methyl-; 2-Methyl-4-butanol; 3-Methylbutan-1-ol; 3-Methylbutanol; 3-Metil-butanolo [Italian]; Alcool amilico [Italian]; Alcool isoamylique [French]; Amylowy alkohol [Polish]; Fermentation amyl alcohol; Fusel Oil; ISOAMYLALCOHOL; Iso-amylalkohol [German]; Isoamyl alcohol (natural); Isoamyl alkohol [Czech]; Isoamylol; Isobutyl carbinol; Isobutylcarbinol; Isopentanol; Isopentyl alcohol; Primary isoamyl alcohol; [ChemIDplus]l

Category

Alcohols (<C12)

Description

Colorless liquid with a disagreeable odor; [NIOSH]

Sources/Uses

Used as a solvent, paint stripper, and intermediate in the photographic and pharmaceutical industries; [ACGIH]

Comments

Rabbits become stuporous after an oral dose of 0.7 g/kg. [ACGIH] A skin, eye, and respiratory tract irritant; May have effects on the CNS if ingested; [ICSC]

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TLV (ACGIH)

100 ppm

STEL (ACGIH)

125 ppm

PEL (OSHA)

100 ppm

MAK

20 ppm

IDLH (NIOSH)

500 ppm

Excerpts from Documentation for IDLHs

An oral dose of 24.3 grams has been lethal for adults [Gosselin et al. 1984]. [Note: An oral dose of 24.3 grams is equivalent to a worker being exposed to 4,000 ppm for 30 minutes, assuming a breathing rate of 50 liters per minute and 100% absorption.]

Vapor Pressure

2.37 mm Hg

Odor Threshold Low

0.02 ppm

Odor Threshold High

0.07 ppm

RD50

4452 ppm

Explanatory Notes

Odor threshold from AIHA; Flash point = 43 deg C;

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: