Agent Name

Fenitrothion

CAS Number

122-14-5

Formula

C9-H12-N-O5-P-S

Major Category

Pesticides

Synonyms

3-Methyl-4-nitrophenyl dimethyl phosphorothioate; 8057HC; AC-47300; Accothion; Agria 1050; Agriya 1050; Agrothion; Akotion; American Cyanamid CL-47,300; Arbogal; BAY 41831; Bayer 41831; Bayer S 5660; C-9146; CL 47300; CP 47114; Cekutrothion; Cyfen; Cytel; Dimethyl (3-methyl-4-nitrophenyl) thiophosphate; Dimethyl 3-methyl-4-nitrophenyl phosphorothionate; Dimethyl 4-nitro-m-tolyl phosphorothionate; Dimethyl-(3-methyl-4-nitrophenyl)thiophosphate; EI 47300; ENT 25,715; Falithion; Fenition; Fenitox; Fenitrotion (Hungarian); Fentrothione; Folithion; Folithion EC 50; Insectigas F; Kotion; MEP (pesticide); Macbar; Metathion; Metathion E 50; Metathione; Metathionine; Metathionine E50; Metation; Metation E50; Methylnitrophos; Mglawik F; Monsanto CP 47114; Nitrophos; Novathion; Nuvanol; O,O-Dimethyl O-(3-methyl-4-nitrophenyl) phosphorothioate; O,O-Dimethyl O-(3-methyl-4-nitrophenyl) phosphorothionate; O,O-Dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate; O,O-Dimethyl O-(4-nitro-3-methylphenyl) thiophosphate; O,O-Dimethyl O-(4-nitro-3-methylphenyl)thiophosphate; O,O-Dimethyl O-4-nitro-m-tolyl phosphorothioate; O,O-Dimethyl-O-(3-methyl-4-nitro-phenyl)-monothiophosphat [German]; O,O-Dimethyl-O-(3-methyl-4-nitrofenyl)-monothiofosfaat [Dutch]; O,O-Dimethyl-O-(4-nitro-5-methylphenyl)-thionophosphat [German]; O,O-Dimetil-O-(3-metil-4-nitro-fenil)-monotiofosfato [Italian]; O,O-Dimetil-O-(3-metil-4-nitrofenil) fosforotioato (Portugese); OMS 43; Oleosumifene; Ovadofos; Owadofos; Owadophos; Pennwalt C-4852; Phenitrothion; Phosphorothioic acid, O,O-dimethyl O-(3-methyl-4-nitrophenyl) ester; Phosphorothioic acid, O,O-dimethyl O-(4-nitro-m-tolyl) ester; S 112A; S-1102A; Sumifene; Sumithion; Sumitomo S-1102A; Super Sumithion; Thiophosphate de O,O-dimethyle et de O-(3-methyl-4-nitrophenyle) [French]; Tionofosforan O,O-dwumetylo-O-(3-metylo)-4-nitrofenylowy [Polish]; Verthion; m-Cresol, 4-nitro-, O-ester with O,O-dimethyl phosphorothioate; [ChemIDplus] UN3018

Category

Organophosphate Insecticides

Description

Yellow liquid; [Merck Index] Brown to yellow liquid; mp = 0.3 deg C; [ICSC] Yellow or yellowish-brown liquid; mp = 3.4 deg C; [HSDB] Brown-yellow liquid; mp = 3.4 deg C; [MSDSonline]

Sources/Uses

Used as insecticide and acaricide for cereals, cotton, orchard fruits, rice, vegetables, forestry, turf, greenhouses, animal houses, public health, and stored products; [HSDB] Used in Australia on stored wheat; Only registered in the US for use in ant and roach bait containers; [Reference #1]

Comments

A skin and eye irritant; Can be absorbed through skin; A cholinesterase inhibitor that may affect the nervous system causing convulsions, respiratory failure, and death; [ICSC] Some evidence of contact dermatitis following exposure; No evidence of delayed neurotoxicity; [HSDB] A very toxic cholinesterase inhibitor that does not cause delayed neurotoxicity; [CAMEO]

Restricted

Banned in the EU for use as pesticide for plant protection; [eChemPortal: ESIS]

Reference Link

EPA Pesticide Chemical Search

Exposure Assessment
BEI

Cholinesterase activity in red cells = 70% of individual's baseline, sample time discretionary; [ACGIH]

Vapor Pressure

5.4E-5 mm Hg

Lethal Concentration

LC50 (rat) > 2,200 mg/m3/4h

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Organophosphorus pesticide, liquid, toxic."

Reference Link

INCHEM JMPR: Fenitrothion - 2000

Adverse Effects
Other Poison

Organophosphate

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

Search ChemIDplus

Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: