Agent Name

Isobutyl acetate

CAS Number

110-19-0

Formula

C6-H12-O2

Major Category

Solvents

Synonyms

2-Methyl-1-propyl acetate; 2-Methylpropyl acetate; 2-Methylpropyl ethanoate; Acetate d'isobutyle [French]; Acetic acid, isobutyl ester; Isobutyl acetate; Isobutyl acetate (natural); Isobutyl ethanoate; Isobutylester kyseliny octove [Czech]; beta-Methylpropyl ethanoate; [ChemIDplus] UN1213

Category

Esters (<C12)

Description

Colorless liquid with a fruity, floral odor; [NIOSH]

Sources/Uses

Solvent uses include nitrocellulose, thinners, sealants, lacquers, and perfumes; [Hawley]

Comments

A skin, eye, and respiratory tract irritant; Inhalation of high concentrations can cause CNS depression; [ICSC]

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TLV (ACGIH)

50 ppm

STEL (ACGIH)

150 ppm

PEL (OSHA)

150 ppm

MAK

100 ppm

IDLH (NIOSH)

1300 ppm

Excerpts from Documentation for IDLHs

Basis for original (SCP) IDLH: The chosen IDLH is based on the following statements: A 4hour exposure to 8,000 ppm killed 4 of 6 rats [UCC 1971; Smyth et al. 1962 as cited by ACGIH 1971] and no deaths resulted from a 4hour exposure of 6 rats to 4,000 ppm [UCC 1971; Smyth 1964 as cited by ACGIH 1971]. . . . Human data: None relevant for use in determining the revised IDLH.

Vapor Pressure

17.8 mm Hg

Odor Threshold Low

0.36 ppm

Odor Threshold High

3.6 ppm

Lethal Concentration

LCLo (rat) = 8,000 ppm/4H

Explanatory Notes

IDLH = 10% LEL; Detection odor threshold from AIHA (mean = 1.1 ppm); Flash point = 18 deg C;

Flammability (NFPA)

3: May ignite at ambient temperature

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Links to Other NLM Databases
Health Studies

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Toxicity Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: