Agent Name

2-Isopropoxyethanol

Alternative Name

EGiPE

CAS Number

109-59-1

Formula

C5-H12-O2

Major Category

Solvents

Synonyms

2-Isopropoxyethanol; Dowanal EiPAT; Ethanol, 2-(1-methylethoxy)-; Ethanol, 2-isopropoxy-; Ethylene glycol isopropyl ether; Ethylene glycol, monoisopropyl ether; Iso-propyl glycol ether; Isopropyl cellosolve; Isopropyl glycol; Isopropyl oxitol; Isopropylethylene glycol ether; Monoisopropyl ether of ethylene glycol; Ucar AC; beta-Hydroxyethyl isopropyl ether; [ChemIDplus]

Category

Glycol Ethers (E Series)

Description

Colorless liquid with a mild, ethereal odor; [NIOSH]

Sources/Uses

Used as a solvent, particularly in paints and lacquers; [ACGIH]

Comments

Osmotic fragility of rat erythrocytes markedly increased at exposures of 200 ppm; [ACGIH] Inhalation of high concentrations can cause CNS depression; [HSDB] May cause skin and eye irritation; [CAMEO] See "Glycol ethers."

Exposure Assessment
Skin Designation (ACGIH)

Yes

TLV (ACGIH)

25 ppm

MAK

5 ppm

Vapor Pressure

1.6 mm Hg

Lethal Concentration

LC50 (rat) = 3,100 mg/m3/4h

Explanatory Notes

Flash point = 33 deg C; VP = 5.2 mm Hg @ 25 deg C; [HSDB]

Adverse Effects
Anemia

Anemia, Hemolytic

Neurotoxin

CNS Solvent Syndrome

Hepatotoxin

Hepatotoxin, Secondary

Nephrotoxin

Yes

Reproductive Toxin

Yes

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

Search ChemIDplus

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: