Agent Name

Isopropyl ether

Alternative Name

Diisopropyl ether

CAS Number

108-20-3

Formula

C6-H14-O

Major Category

Solvents

Synonyms

2,2'-Oxybis-propane; 2-Isopropoxypropane; Bis(isopropyl) ether; Diisopropyl ether; Diisopropyl oxide; Ether isopropylique [French]; Ether, isopropyl; Izopropylowy eter [Polish]; Propane, 2,2'-oxybis-; [ChemIDplus] UN1159

Category

Ethers (<C12)

Description

Colorless liquid with a sharp, sweet, ether-like odor; [NIOSH]

Sources/Uses

Used as a solvent for resins, waxes, oils, dyes, and surface coatings; [ACGIH]

Comments

The odor is "more irritating and less pleasant than that of ethyl ether." [ACGIH] A skin, eye, and respiratory tract irritant; Inhalation of high concentrations can cause CNS depression; [ICSC]

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TLV (ACGIH)

250 ppm

STEL (ACGIH)

310 ppm

PEL (OSHA)

500 ppm

MAK

200 ppm

IDLH (NIOSH)

1400 ppm

Excerpts from Documentation for IDLHs

Volunteers exposed to 800 ppm for 5 minutes reported irritation of the eyes and nose [Silverman et al. 1946].

Vapor Pressure

149 mm Hg

Odor Threshold Low

0.01 ppm

Odor Threshold High

0.05 ppm

Lethal Concentration

LC50 (rat) = 162,000 mg/m3

Explanatory Notes

IDLH = 10% LEL; Detection odor threshold from AIHA (mean = 0.017 ppm); Flash point = -28 deg C;

Flammability (NFPA)

3: May ignite at ambient temperature

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: