Agent Name

N-Isopropylaniline

CAS Number

768-52-5

Formula

C9-H13-N

Major Category

Nitrogen Compounds

Synonyms

N-IPA; Isopropylaniline; N-(1-Methylethyl)benzenamine; N-Phenylisopropylamine; [NIOSH]

Category

Amines, Aromatic

Description

Clear, yellowish liquid with a sweet, aromatic odor; [NIOSH]

Sources/Uses

Used in synthesis of dyes for acrylic fibers and other chemicals; [ACGIH]

Comments

Like aniline and N,N-dimethylaniline, N-isopropylaniline can cause methemoglobinemia after skin and inhalation exposure in the workplace. [ACGIH] Can induce methemoglobinemia; May cause skin sensitization; [ICSC]

Exposure Assessment
BEI

Methemoglobin in blood = 1.5% of hemoglobin during or at end of shift. [ACGIH]

Skin Designation (ACGIH)

Yes

TLV (ACGIH)

2 ppm

Vapor Pressure

0.44 mm Hg

Lethal Concentration

LC50 (rat) = 1,100 mg/m3/4h

Explanatory Notes

Flash point = 87 deg C;

Adverse Effects
Skin Sensitizer

Yes

Methemoglobinemia

Methemoglobinemia, Primary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: