Agent Name

Fosthietan

CAS Number

21548-32-3

Formula

C6-H12-N-O3-P-S2

Major Category

Pesticides

Synonyms

(Diethoxyphosphinylimino)-1,3-dithietane; 1,3-Dithietan-2-ylidenephosphoramidic acid diethyl ester; 2-(Diethoxyphosphinylimino)-1,3-dithietane; AC 64475; Acconem; CL 64475; Cyclic methylene (diethoxyphosphinyl)dithio-imidocarbonate; Cyclic methylene diethoxyphosphinodithioimidocarbonate; Cyclic methylene(diethoxyphosphinyl)dithioiminocarbonate; Diethoxyphosphinylimido-1,3-dithiethane; Diethoxyphosphinylimino-2 dithietanne-1,3 [French]; Diethyl 1,3-dithietan-2-ylidenephosphoramidate; Diethyl 1,3-dithiethane-2-ylidene-phosphoramidate; ENT 27,873; Fosthietan [ANSI]; Geofos; Imidocarbonic acid, phosphonodithio-, cyclic methylene P,P-diethyl ester (8CI); Nem-A-Tak; Phosphonodithioimidocarbonic acid cyclic methylene P,P-diethyl ester; Phosphoramidic acid, 1,3-dithietan-2-ylidene-, diethyl ester; [ChemIDplus]

Category

Organophosphate Insecticides

Description

Pale yellow liquid; [HSDB]

Sources/Uses

Used as soil insecticide and nematicide; [HSDB]

Comments

A cholinesterase inhibitor; Can be absorbed through skin; [CAMEO] The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline. [TLVs and BEIs]

Restricted

Not currently registered as a pesticide for use in the US; [HSDB]

Exposure Assessment
BEI

Acetylcholinesterase activity in red blood cells = 70% of individual's baseline; Butylcholinesterase activity in serum or plasma = 60% of individual's baseline; Sample at end of shift; [TLVs and BEIs]

Vapor Pressure

6.45E-6 mm Hg

Adverse Effects
Other Poison

Organophosphate

Links to Other NLM Databases
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Chemical Information

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Diseases

Occupational diseases associated with exposure to this agent:

Processes

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