Agent Name

Manganese cyclopentadienyl tricarbonyl

CAS Number

12079-65-1

Formula

C8-H5-Mn-O3

Major Category

Metals

Synonyms

Cyclopentadienylmanganese tricarbonyl; Cyclopentadienyl tricarbonyl manganese; MCT; [NIOSH]

Category

Metals, Organic Compounds

Description

Yellow, crystalline solid with a characteristic odor. [Note: An antiknock additive for gasoline. May be found in an oil & gaseous solution.] [NIOSH]

Sources/Uses

Used as an anti-knock agent in unleaded gasoline--this use not permitted in the U.S.A. since 1981; [ACGIH]

Comments

Injected doses of 20 mg/kg cause convulsions and pulmonary edema in rats. MCT was estimated to be twice as toxic to the lung as MMT (methylcyclopentadienyl manganese tricarbonyl). In chronic inhalation studies, rats showed no outward signs of disease during the exposure period (averaging 1 mg/m3 for 4 hours/day for 11 months), but increased excitability of the nervous system was detected with electrical studies after 7 months of exposure. [ACGIH] See "Manganese" and linked occupational diseases.

Exposure Assessment
Skin Designation (ACGIH)

Yes

Bioaccumulates

Yes

TLV (ACGIH)

0.1 mg/m3, as Mn

PEL (OSHA)

Ceiling(OSHA) = 5 mg/m3, as Mn

MAK

0.2 mg/m3, as Mn, (inhalable fraction), 0.02 mg/m3, as Mn (respirable fraction)

Explanatory Notes

Sublimes at 75-77 deg C; [CAMEO]

Adverse Effects
Neurotoxin

Other CNS Neurotoxin

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: