Agent Name

Hexadecyltrichlorosilane

CAS Number

5894-60-0

Formula

C16-H33-Cl3-Si

Major Category

Toxic Gases & Vapors

Synonyms

Hexadecyl trichlorosilane; Hexadecyltrichlorosilane(DOT); Silane, hexadecyltrichloro-; Silane, trichlorohexadecyl-; [ChemIDplus] UN1781

Category

Chlorosilanes

Description

Colorless to yellow liquid; [Hawley] Clear colorless liquid; [MSDSonline]

Sources/Uses

Used to make silicones; [Hawley]

Comments

Highly irritating; Contact with moisture produces hydrogen chloride; [Hawley] Produces hydrogen chloride when spilled in water; [ERG 2016] A corrosive substance that can cause injury to the skin, eyes, and mucous membranes; [HSDB] Reacts violently with water evolving heat, hydrogen (combustible), and hydrogen chloride (corrosive); Produces hydrogen chloride on contact with air; Corrosive to tissue; [CAMEO] Reacts violently with water; A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; Inhalation may cause chemical pneumonitis; [MSDSonline]

Exposure Assessment
TIH

Yes

Dangerous When Wet

Yes - A material that, by contact with water, is liable to become spontaneously flammable or to give off flammable or toxic gas at a rate greater than 1 L per kilogram of the material, per hour; [ERG 2004]

Explanatory Notes

Not TIH in land-based spills, but TiH substance released when spilled in water; [ERG 2016]

Adverse Effects
Toxic Pneumonitis

Yes

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: