Agent Name

Methyl isobutyl carbinol

Alternative Name

Methyl amyl alcohol

CAS Number

108-11-2

Formula

C6-H14-O

Major Category

Solvents

Synonyms

Methyl amyl alcohol; (+-)-4-Methyl-2-pentanol; 1,3-Dimethylbutanol; 2-Methyl-4-pentanol; 2-Pentanol, 4-methyl-; 3-MIC; 4-Methyl-2-amyl alcohol; 4-Methyl-2-pentyl alcohol; 4-Methylpentanol-2; 4-Metilpentan-2-olo [Italian]; 4-Pentanol, 2-methyl-; Alcohol methyl amylique [French]; Alcool methyl amylique [French]; Isobutylmethylcarbinol; Isobutylmethylmethanol; M.I.B.C.; MAOH; MIBC; MIC; Methyl amyl alcohol; Methyl isobutyl carbinol; Methyl-isobutylkarbinol [Czech]; Methylisobutyl carbinol; Methylisobutylcarbinol; Metilamil alcohol [Italian]; dl-Methylisobutylcarbinol; [ChemIDplus] UN2053

Category

Alcohols (<C12)

Description

Colorless liquid with a mild odor; [NIOSH]

Sources/Uses

Used as a solvent for dyestuffs, oils, gums, resins, waxes, etc.; [ACGIH] Used to make lacquers, solvents, plasticizers, and lubricants; [HSDB]

Comments

In acute animal studies, high concentrations induce narcosis and anesthesia. [ACGIH] Inhalation of high concentrations can cause CNS depression; A skin, eye, and respiratory tract irritant; [ICSC]

Exposure Assessment
Skin Designation (ACGIH)

Yes

TLV (ACGIH)

25 ppm

STEL (ACGIH)

40 ppm

PEL (OSHA)

25 ppm

MAK

20 ppm

IDLH (NIOSH)

400 ppm

Excerpts from Documentation for IDLHs

Human data: Eye irritation has occurred after exposures to 50 ppm for 15 minutes [Silverman et al. 1946].

Vapor Pressure

5.3 mm Hg

Odor Threshold Low

0.01 ppm

Odor Threshold High

1 ppm

Lethal Concentration

LCLo (rat) = 2,000 ppm/4H

Explanatory Notes

Odor threshold from "Quick Guide: The Electronic NIOSH Pocket Guide to Chemical Hazards"; Flash point = 105 deg F;

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: