Agent Name

Methylacrylonitrile

Alternative Name

Methacrylonitrile

CAS Number

126-98-7

Formula

C4-H5-N

Major Category

Nitrogen Compounds

Synonyms

Methacrylonitrile; 2-Cyanopropene-1; 2-Methyl-2-propenenitrile; 2-Methylacrylonitrile; 2-Methylpropenenitrile; 2-Propenenitrile, 2-methyl-; Isopropene cyanide; Isopropenylnitrile; Methylacrylonitrile; [ChemIDplus] UN3079

Category

Nitriles

Description

Colorless liquid with an odor like bitter almonds; [NIOSH]

Sources/Uses

Used in synthesis of plastic elastomers, coatings, and other organic chemicals; [ACGIH]

Comments

Inhalation toxicity is comparable to that of acrylonitrile; Causes paralysis of hind limbs and seizures in dogs exposed to 13.5 ppm for 90 days; [ACGIH] An eye and respiratory tract irritant; Can cause cyanide poisoning; [ICSC] A skin sensitizer; [Quick CPC] A lachrymator; [HSDB]

Exposure Assessment
Skin Designation (ACGIH)

Yes

TIH

Yes

TLV (ACGIH)

1 ppm

Excerpts from Documentation for IDLHs

Acute inhalation toxicity is similar to acrylonitrile; [ACGIH]

Vapor Pressure

71 mm Hg

Odor Threshold Low

6.9 ppm

Lethal Concentration

LC50 (rat) = 328 ppm/4h

Explanatory Notes

Detection odor threshold from AIHA (mean = 6.9 ppm); Flash point = 13 deg C;

Flammability (NFPA)

3: May ignite at ambient temperature

Adverse Effects
Skin Sensitizer

Yes

Lacrimator

Yes

Other Poison

Chemical Asphyxiant

ACGIH Carcinogen

Not Classifiable

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: