Agent Name

Methylacrylonitrile

Alternative Name

Methacrylonitrile

CAS Number

126-98-7

Formula

C4-H5-N

Major Category

Nitrogen Compounds

Synonyms

Methacrylonitrile; 2-Cyanopropene-1; 2-Methyl-2-propenenitrile; 2-Methylacrylonitrile; 2-Methylpropenenitrile; 2-Propenenitrile, 2-methyl-; Isopropene cyanide; Isopropenylnitrile; Methylacrylonitrile; [ChemIDplus] UN3079

Category

Nitriles

Description

Colorless liquid with an odor like bitter almonds; [NIOSH]

Sources/Uses

Used in synthesis of plastic elastomers, coatings, and other organic chemicals; [ACGIH]

Comments

Inhalation toxicity is comparable to that of acrylonitrile; Causes paralysis of hind limbs and seizures in dogs exposed to 13.5 ppm for 90 days; [ACGIH] An eye and respiratory tract irritant; Can cause cyanide poisoning; [ICSC] A skin sensitizer; [Quick CPC] A lachrymator; [HSDB] Methacrylonitrile, stabilized (UN3079) has warning of explosive polymerization; [ERG 2016]

Exposure Assessment
Skin Designation (ACGIH)

Yes

TIH

Yes

TLV (ACGIH)

1 ppm

IDLH (NIOSH)

4 ppm

Excerpts from Documentation for IDLHs

Acute inhalation toxicity is similar to acrylonitrile; [ACGIH]

Vapor Pressure

71 mm Hg

Odor Threshold Low

6.9 ppm

Lethal Concentration

LC50 (rat) = 328 ppm/4h

Explosive Polymerization

Yes

Explanatory Notes

Detection odor threshold from AIHA (mean = 6.9 ppm); Flash point = 13 deg C;

Adverse Effects
Skin Sensitizer

Yes

Lacrimator

Yes

Other Poison

Chemical Asphyxiant

ACGIH Carcinogen

Not Classifiable

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: