Agent Name

Tri-n-butyltin hydride

Alternative Name

Tributyltin

CAS Number

688-73-3

Formula

C12-H28-Sn

Major Category

Metals

Synonyms

Stannane, tributyl-; Tin, tri-n-butyl-, hydride; Tri-n-butylstannane hydride; Tributylstannane; Tributylstannic hydride; Tributyltin; Tributyltin hydride; [ChemIDplus] UN2788

Category

Tin Compounds, Organic

Description

Liquid; [Hawley] Colorless liquid; [MSDSonline]

Sources/Uses

Used as a biocide in paints for ships and fishnets; [ChemIDplus] Used as a reducing agent for the conversion of alkyl halides to hydrocarbons, a veterinary anthelmintic for poultry, and an intermediate to make other butyltin compounds; Use as a marine biocide is being phased out globally due to toxicity to aquatic organisms. [HSDB]

Comments

In inhalation lethal dose studies, causes lacrimation, dyspnea, and seizures; [ChemIDplus] Can cause skin burns; [Sullivan, p. 979] A skin and eye irritant; [eChemPortal: ERMA] Produces flammable gases on contact with water; An irritant; Can be absorbed through skin; [MSDSonline] See "ORGANOMETALS." See "Tin, organic compounds."

Reference Link

EXTOXNET PIP - TRIBUTYLTIN (TBT)

Exposure Assessment
Skin Designation (ACGIH)

Yes

TLV (ACGIH)

0.1 mg/m3, as Sn

STEL (ACGIH)

0.2 mg/m3, as Sn

PEL (OSHA)

0.1 mg/m3, as Sn

MAK

0.02 mg/m3, inhalable fraction, as Sn

IDLH (NIOSH)

25 mg/m3, as Sn

Lethal Concentration

LCLo (rat) = 1,460 mg/m3/10min

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Organotin compound, liquid, n.o.s." Organic tin compounds have a "skin" designation and are classified as "A4" (Not classifiable as human carcinogen); [ACGIH]

Adverse Effects
Neurotoxin

Other CNS Neurotoxin

Hepatotoxin

Hepatotoxin, Secondary

Dermatotoxin

Skin Burns

ACGIH Carcinogen

Not Classifiable

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Biomedical References

Search PubMed

Related Information in HazMap
Processes

Industrial Processes with risk of exposure: