Agent Name

alpha-Methyl styrene

CAS Number

98-83-9

Formula

C9-H10

Major Category

Plastics & Rubber

Synonyms

1-Methyl-1-phenylethene; 1-Methyl-1-phenylethylene; 1-MethylethenylBenzine; 1-Methylethylenebenzene; 1-Phenyl-1-methylethylene; 1-Propene, 2-phenyl-; 2-Phenyl-1-propene; 2-Phenylpropene; 2-Phenylpropylene; Benzene, (1-methylethenyl)-;Isopropenil-benzolo [Italian]; Isopropenyl-benzeen [Dutch]; Isopropenyl-benzol [German]; Isopropenylbenzene; alpha-Methyl-styrol [German]; alpha-Methylstyreen [Dutch]; alpha-Methylstyrene; alpha-Methylstyrol; alpha-Metil-stirolo [Italian]; as-Methylphenylethylene; beta-Phenylpropene; beta-Phenylpropylene; [ChemIDplus] UN2303; UN1993

Category

Styrenes

Description

Colorless liquid with a characteristic odor; [NIOSH]

Sources/Uses

Used as a polymerization monomer; [ACGIH]

Comments

Human subjects complained of an unpleasant odor and mild eye irritation. CNS depression possible after absorption of sufficient dose; TLV Basis: Irritation; Kidney & female reproductive damage; [ACGIH] A lachrymator; [CHEMINFO] A skin, eye, and respiratory tract irritant; Causes lachrymation; [ICSC]

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TLV (ACGIH)

10 ppm

PEL (OSHA)

Ceiling(OSHA) = 100 ppm

MAK

50 ppm

IDLH (NIOSH)

700 ppm

Excerpts from Documentation for IDLHs

Other animal data: A considerable number of rats and guinea pigs exposed to 3,000 ppm for 7 to 8 hours/day, 5 days/week for up to 6 months died [Gerarde 1960; Wolf et al. 1956]. Rats and guinea pigs had slight changes in liver and kidney weights and some reduction in body weight following exposure to 800 ppm for 7 hours/day, 5 days/week for 27 days [Wolf et al. 1956]. No adverse effects were noted in rats, rabbits, mice, monkeys, and guinea pigs exposed 7 hours/day, 5 days/week for 5 months to 200 ppm [Wolf et al. 1956]. . . . Human data: Four volunteers reported a definite unpleasant odor and slight eye irritation after about 2 minutes of exposure to 200 ppm [Wolf et al. 1956]. Strong eye and nasal irritation has been noted at concentrations above 600 ppm [Gerarde 1960; Wolf et al. 1956].

Vapor Pressure

2 mm Hg

Odor Threshold Low

0.05 ppm

Odor Threshold High

0.16 ppm

Lethal Concentration

LCLo (rat) = 3,000 ppm

Explanatory Notes

Odor threshold (detection at 0.052 ppm and recognition at 0.16 ppm) from CHEMINFO; Flash point = 84 deg C;

Adverse Effects
Lacrimator

Yes

Neurotoxin

CNS Solvent Syndrome

Reproductive Toxin

Yes

IARC Carcinogen

Possible Carcinogen

ACGIH Carcinogen

Confirmed Animal

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

Search ChemIDplus

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: