Agent Name

Methylcyclohexane

CAS Number

108-87-2

Formula

C7-H14

Major Category

Solvents

Synonyms

Cyclohexane, methyl-; Cyclohexylmethane;Hexahydrotoluene; Hexahydroxytoluene; Methylcyclohexane; Metylocykloheksan [Polish]; Sextone B; Toluene hexahydride; Toluene, hexahydro-; [ChemIDplus] UN2296

Category

Aliphatics, Saturated (<C12)

Description

Colorless liquid with a faint, benzene-like odor; [NIOSH]

Sources/Uses

Used in organic synthesis, as a solvent for cellulose ethers, and in jet fuel. [ACGIH]

Comments

Slight histopathological changes in the kidney and liver seen in subchronically exposed experimental animals; [ACGIH] A skin and eye irritant; Inhalation of high concentrations can cause CNS depression; [ICSC]

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TLV (ACGIH)

400 ppm

PEL (OSHA)

500 ppm

MAK

200 ppm

IDLH (NIOSH)

1200 ppm

Excerpts from Documentation for IDLHs

Basis for original (SCP) IDLH: With no reported human toxicological data, the chosen IDLH is based on the statement by Browning [1965] that Treon et al. [1943] were able to produce light narcosis in mice at 10,054 ppm. Browning [1965] also reported that Lazarew [1929] found the narcotic dose for mice to be 7,500 to 10,000 ppm. ACGIH [1971] noted that this narcotic dose (7,500 to 10,000 ppm) was for a 2hour exposure [Lazarew 1929; Treon et al. 1943]. . . . Human data: None relevant for use in determining the revised IDLH.

Vapor Pressure

46 mm Hg

Odor Threshold Low

500 ppm

Lethal Concentration

LCLo (rat) = 82,000 mg/m3/1H

Explanatory Notes

IDLH = 10% LEL; Odor threshold from CHEMINFO; Flash point = -4 deg C;

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Hepatotoxin

Hepatotoxin, Secondary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: