Agent Name

o-Methylcyclohexanone

CAS Number

583-60-8

Formula

C7-H12-O

Major Category

Solvents

Synonyms

2-Methyl-1-cyclohexanone; 2-Methyl-cyclohexanon [German, Dutch]; 2-Methylcyclohexanone; 2-Metilcicloesanone [Italian]; Methylanon; Sexton B; alpha-Methylcyclohexanone; o-Methylcyclohexanone; [ChemIDplus] UN2297

Category

Ketones (<C12)

Description

Colorless liquid with a weak, peppermint-like odor; [NIOSH]

Sources/Uses

Used as a rust remover and a solvent to make lacquers, varnishes, and plastics; Used in the leather industry; [ACGIH]

Comments

Narcosis occurs in animal inhalation studies; [ACGIH] A skin, eye, and respiratory tract irritant; [CAMEO]

Exposure Assessment
Skin Designation (ACGIH)

Yes

TLV (ACGIH)

50 ppm

STEL (ACGIH)

75 ppm

PEL (OSHA)

100 ppm

IDLH (NIOSH)

600 ppm

Excerpts from Documentation for IDLHs

Other animal data: Mice, guinea pigs, and rats exposed at 3,500 ppm for 30 minutes suffered irritation of the mucous membranes and exhibited signs of central nervous system depression [Clayton and Clayton 1981]. Rabbits and cats exhibited sleepiness, respiratory irregularities, and poor coordination after a 1hour exposure to 2,500 ppm [Clayton and Clayton 1981].

Vapor Pressure

2.25 mm Hg

Odor Threshold Low

0.5 ppm

Lethal Concentration

LCLo (rat) = 2,800 ppm/4H

Explanatory Notes

Flash point = 118 deg F; Odor threshold from CHEMINFO;

Flammability (NFPA)

2: High ambient temperature required

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

Search ChemIDplus

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: