Agent Name

Hymenoxone

CAS Number

57377-32-9

Formula

C15-H22-O5

Major Category

Biological Agents

Synonyms

Hymenoxon; Furo(2',3':5,6)cyclohepta(1,2-c)pyran-2(3H)-one, decahydro-5,7-dihydroxy-4a,9-dimethyl-3-methylene-, (3aR,4aS,5R,7R,8aR,9R,10aR)-; Furo(2',3':5,6)cyclohepta(1,2-c)pyran-2(3H)-one, decahydro-5,7-dihydroxy-4a,9-dimethyl-3-methylene-, (3aR-(3a-alpha,4a-beta,5-alpha,7-beta,8a-alpha,9-alpha,10a-alpha))-; [ChemIDplus]

Category

Plant Toxins

Sources/Uses

Toxic constituent of Hymenoxys odorata (bitterweed), Helenium hoopsii, and Baileya multiradiata (poisonous range plants); [HSDB]

Comments

Emergency treatment: "Plants- sesquiterpene lactones"; Sesquiterpene lactones are in many plants. They cause toxicity mainly in livestock that eat the plants. Human poisoning cases are extremely rare. Possible symptoms after ingestion include irritation of mucous membranes, dyspnea, pulmonary hemorrhage, tremors, seizures, abdominal pain, and liver injury. [HSDB] Sesquiterpene lactones are a common cause of allergic dermatitis in florists. See "Sesquiterpene lactones."

Adverse Effects
Skin Sensitizer

Yes

Neurotoxin

Other CNS Neurotoxin

Hepatotoxin

Hepatotoxin, Secondary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: