Agent Name

Picric acid

Alternative Name

2,4,6-Trinitrophenol

CAS Number

88-89-1

Formula

C6-H3-N3-O7

Major Category

Other Uses

Synonyms

1,3,5-Trinitrophenol; 2,4,6-Trinitrofenol [Dutch]; 2,4,6-Trinitrofenolo [Italian]; 2,4,6-Trinitrophenol; 2-Hydroxy-1,3,5-trinitrobenzene; Acide picrique [French]; Acido picrico [Italian]; Acidum picrinicum; C.I. 10305; CI 10305; Carbazotic acid; Kyselina pikrova [Czech]; Melinite; Nitroxanthic acid; Phenol trinitrate; Phenoltrinitrate; Picral; Picronitric acid; Pikrinezuur [Dutch]; Pikrinsaeure [German]; Pikrynowy kwas [Polish]; Trinitrophenol; [ChemIDplus]

Category

Explosives

Description

Yellow, odorless solid. [Note: Usually used as an aqueous solution.]; [NIOSH]

Sources/Uses

Used as an explosive, dye, fungicide, copper etching agent, and chemical intermediate for metal picrates; it is used in the manufacturing of leather products, batteries, colored glass, textile mordants, rocket fuel, and photographic emulsions; [HSDB]

Comments

Workers may develop skin sensitization. Laboratory dogs receiving subcutaneously 100-125 mg/kg die of respiratory paralysis and have liver abnormalities on pathological examination. [HSDB] Irritating to the skin, eyes, and respiratory tract; May stain yellow the hair and skin; [ICSC]

Restricted

An OSHA Class A Explosive (1910.109)

Reference Link

Allergic contact dermatitis from picric acid

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TLV (ACGIH)

0.01 ppm

PEL (OSHA)

0.01 ppm

IDLH (NIOSH)

8 ppm

Excerpts from Documentation for IDLHs

Human data: The ingestion of 1 to 2 grams of picric acid has been reported to cause severe poisoning [ACGIH 1991]. [Note: An oral dose of 1 to 2 grams is equivalent to a worker being exposed to 660 to 1,330 mg/m3 for 30 minutes, assuming a breathing rate of 50 liters per minute and 100% absorption.]

Vapor Pressure

7.5E-7 mm Hg

Reference Link

ICSC: Picric acid

Flammability (NFPA)

4: Burns readily

Adverse Effects
Nephrotoxin

Yes

Skin Sensitizer

Yes

Hepatotoxin

Hepatotoxin, Secondary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: