Agent Name

Imperatorin

CAS Number

482-44-0

Formula

C16-H14-O4

Major Category

Biological Agents

Synonyms

5-Benzofuranacrylic acid, 6-hydroxy-7-((3-methyl-2-butenyl)oxy)-, delta-lactone; 6-Hydroxy-7-(3-methyl-2-butenyloxy)-5-benzofuranacrylic acid omega-lactone; 7H-Furo(3,2-g)(1)benzopyran-7-one, 9-((3-methyl-2-butenyl)oxy)-; 8-Isoamylenoxypsoralen; 8-Isopentenyloxypsoralene; 9-((3-Methyl-2-butenyl)oxy)-7H-furo(3,2-g)(1)benzopyran-7-one; 9-(3-Methylbut-2-enyloxy)furo(3,2-g)chromen-7-one; Ammidin; Marmelosin; Pentosalen; [ChemIDplus]

Category

Plant Oils and Extracts

Description

Solid; [Merck Index]

Sources/Uses

Found in the roots of Imperatoria osthruthium, seeds of Angelica archangelica, and fruit of Pastinaca sativa; [Merck Index] Dried substance and derivatives used in liqueurs (bitters); [HSDB] A naturally occurring psoralen; [REPROTOX]

Comments

Emergency treatment: "Psoralens"; Therapeutic doses (with UV light) are 0.6 mg/kg; Hepatitis has been reported after ingestion of herbal remedies and use of psoralen-UV therapy; [HSDB] May cause irritation; [MSDSonline] See "Angelicin."

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

Dermatotoxin

Contact Dermatitis, Photoirritant

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Toxicity Information

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Chemical Information

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Diseases

Occupational diseases associated with exposure to this agent: