Agent Name

Monocrotophos

Alternative Name

Azodrin

CAS Number

6923-22-4

Formula

C7-H14-N-O5-P

Major Category

Pesticides

Synonyms

Azodrin; (E)-Dimethyl 1-methyl-3-(methylamino)-3-oxo-1-propenyl phosphate; 3-(Dimethoxyphosphinyloxy)N-methyl-cis-crotonamide; 3-Dimethoxyphosphinoyloxy-N-methylisocrotonamide; 3-Hydroxy-N-methyl-cis-crotonamide dimethyl phosphate ester; Aimocron; Apadrin; Azodrin; Azodrin 202R; Azodrin insecticide; Azodrin-71; Biloborn; Bilobran; C 1414; Ciba 1414; Corophos; Crisodrin; Croton 36; Crotonamide, 3-hydroxy-N-methyl-, dimethylphosphate, (E)-; Crotos; Dimethyl (E)-1-methyl-2-(methylcarbamoyl)vinyl phosphate; Dimethyl (E)-3-hydroxy-N-methylcrotonamide; Dimethyl 1-methyl-2-(methylcarbamoyl)vinyl phosphate, cis; Dimethyl phosphate ester of 3-hydroxy-N-methyl-cis-crotonamide; Dimethyl phosphate ester with (E)-3-hydroxy-N-methylcrotonamide; Dimethyl phosphate of 3-hydroxy-N-methyl-cis-crotonamide; Glore phos 36; Hazodrin; Monocil; Monocil 40; Monocron; Monocrotophos 40 EC; Monodrin; Monokrotofosz (Hungarian); Monostar; N-Desmethyl bidrin; Nuvacron; Nuvacron 20; O,O-Dimethyl cis-1-methyl-2-methylcarbamoylvinylphosphate; O,O-Dimethyl-O-(1-methyl-2-N-methyl-carbamoyl)-vinyl-phosphat [German]; O,O-Dimethyl-O-(2-N-methylcarbamoyl-1-methyl)-vinyl-phosphat [German]; O,O-Dimethyl-O-(2-N-methylcarbamoyl-1-methyl-vinyl) phosphate; O,O-Dimethyl-O-(2-N-methylcarbamoyl-1-methyl-vinyl)-fosfaat [Dutch]; O,O-Dimetil-O-(2-N-metilcarbamoil-1-metil-vinil)-fosfato [Italian]; OMS 834; Pandar; Parryfos; Phosphate de dimethyle et de 2-methylcarbamoyl 1-methylvinyle [French]; Phosphoric acid, dimethyl 1-methyl-3-(methylamino)-3-oxo-1-propenyl ester, (E)-; Phosphoric acid, dimethyl ester, ester with (E)-3-hydroxy-N-methylcrotonamide; Phosphoric acid, dimethyl ester, ester with 3-hydroxy-N-methylcrotonamide, (E)-; Phosphoric acid, dimethyl ester, ester with cis-3-hydroxy-N-methylcrotonamide; Pillardrin; Plantdrin; Rapid X; SD 9129; Shell SD 9129; Susvin; Ulvair; cis-1-Methyl-2-methyl carbamoyl vinyl phosphate; [ChemIDplus]

Category

Organophosphate Insecticides

Description

Colorless to reddish-brown solid with a mild, ester odor. [insecticide]; [NIOSH]

Sources/Uses

Used to kill insects and spider mites on cotton, sugarcane, peanuts, tobacco, and ornamentals; very toxic to birds and mammals. [EXTOXNET]

Comments

Inhalation of high concentrations may cause CNS effects; Cholinesterase inhibitor; [ICSC] The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline. [TLVs and BEIs]

Restricted

All uses cancelled by the EPA in 1988; [EXTOXNET]

Reference Link

EXTOXNET PIP - MONOCROTOPHOS

Exposure Assessment
BEI

Acetylcholinesterase activity in red blood cells = 70% of individual's baseline; Butylcholinesterase activity in serum or plasma = 60% of individual's baseline; Sample at end of shift; [TLVs and BEIs]

Skin Designation (ACGIH)

Yes

TLV (ACGIH)

0.05 mg/m3, inhalable fraction and vapor

Vapor Pressure

7.0E-6 mm Hg

Lethal Concentration

LC50 (rat) = 63 mg/m3/4h

Adverse Effects
Other Poison

Organophosphate

ACGIH Carcinogen

Not Classifiable

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

Search ChemIDplus

Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: