Agent Name

3,4-Dichlorophenyl isocyanate

CAS Number

102-36-3

Formula

C7-H3-Cl2-N-O

Major Category

Toxic Gases & Vapors

Synonyms

1,2-Dichloro-4-isocyanatobenzene; 3,4-Dichlorfenylisokyanat [Czech]; Benzene, 1,2-dichloro-4-isocyanato-; Isocyanic acid, 3,4-dichlorophenyl ester; [ChemIDplus] UN2250

Category

Monoisocyanates

Description

White to yellow solid; [HSDB] White crystalline solid; [MSDSonline]

Sources/Uses

Used in organic synthesis; [Hawley]

Comments

An irritant that can cause acute inhalation injury; Acute pneumonitis is the most immediate serious effect after isocyanate exposure; [HSDB] Highly irritating to tissue; [CAMEO] May cause skin sensitization based on animal studies; [IUCLID] A lachrymator; [CHEMINFO] An irritant; A lachrymator; No sensitizing effects known; [MSDSonline] See "MONOISOCYANATES."

Exposure Assessment
Lethal Concentration

LC50 (rat) = 2,700 mg/m3/4H

Explanatory Notes

Vapor pressure = 0.56 mm Hg at 43 deg C; [ChemIDplus] The Guide in the Emergency Response Guidebook is for "Dichlorophenyl isocyanates."

Adverse Effects
Lacrimator

Yes

Toxic Pneumonitis

Yes

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Other Information

No other related information on this agent was found.