Agent Name

4-Chlorophenyl isocyanate

CAS Number

104-12-1

Formula

C7-H4-Cl-N-O

Major Category

Toxic Gases & Vapors

Synonyms

Isocyanic acid, p-chlorophenyl ester; 1-Chloro-4-isocyanatobenzene; 4-Chloroisocyanatobenzene; Benzene, 1-chloro-4-isocyanato-; PCPI; p-Chlorfenylisokyanat [Czech]; p-Chlorophenyl isocyanate; para-Chlorophenyl isocyanate; [ChemIDplus] UN2811

Category

Monoisocyanates

Description

Colorless to yellow liquid or white solid; [Hawley] White crystalline solid; mp = 29-31 deg C; [MSDSonline]

Sources/Uses

Used to produce pharmaceuticals and pesticides; [Hawley]

Comments

A strong irritant of the skin and eyes; [Hawley] An irritant; May cause lacrimation and serious injury to eyes; May cause respiratory sensitization after prolonged contact; [MSDSonline] Could be carcinogenic for man but not conclusive because of insufficient data (3B); [MAK] See "MONOISOCYANATES."

Exposure Assessment
Vapor Pressure

95.4 mm Hg

Lethal Concentration

LC50 (rat) = 113 mg/m3/4h

Explanatory Notes

Flash point = 110 deg C; [Hawley] The Guide in the Emergency Response Guidebook is for "Toxic solid, organic, n.o.s."

Adverse Effects
Lacrimator

Yes

Toxic Pneumonitis

Yes

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Other Information

No other related information on this agent was found.