Agent Name

Isopropyl chloroformate

CAS Number

108-23-6

Formula

C4-H7-Cl-O2

Major Category

Toxic Gases & Vapors

Synonyms

Carbonochloride acid, 1-methylethyl ester; Carbonochloridic acid, 1-methylethyl ester; Chloroformic acid isopropyl ester; Formic acid, chloro-, isopropyl ester; Isopropyl chlorocarbonate; Isopropyl chloromethanoate; Isopropylester kyseliny chlormravenci [Czech]; [ChemIDplus] UN2407

Category

Acid Halides

Description

Clear liquid with an irritating odor; [CAMEO] Reacts with water evolving hydrogen chloride; [ICSC]

Sources/Uses

Used in organic synthesis; [CAMEO]

Comments

A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; Inhalation can cause pulmonary edema; "Causes watering of the eyes." [ICSC] A skin, eye, and respiratory tract irritant; May cause pulmonary edema; [HSDB] See "CHLOROFORMATES."

Exposure Assessment
TIH

Yes

Lethal Concentration

LCLo (rat) = 200 ppm/5h

Explanatory Notes

VP = 100 mm Hg at 47 deg C; [HSDB]

Flammability (NFPA)

3: May ignite at ambient temperature

Adverse Effects
Lacrimator

Yes

Toxic Pneumonitis

Yes

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

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Toxicity Information

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Chemical Information

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Diseases

Occupational diseases associated with exposure to this agent: