Agent Name

Isovaleric acid

CAS Number

503-74-2

Formula

C5-H10-O2

Major Category

Other Classes

Synonyms

3-Methylbutanoic acid; 3-Methylbutyrate; 3-Methylbutyric acid; Acetic acid, isopropyl-; Butanoic acid, 3-methyl-; Butyric acid, 3-methyl-; Delphinic acid; Isobutyl formic acid; Isobutylformic acid; Isopentanoic acid; Isopropylacetic acid; Isovalerianic acid; Isovaleric acid (natural); Kyselina isovalerova [Czech]; beta-Methylbutyric acid; [ChemIDplus]

Category

Organic Acids

Description

Liquid with a disagreeable odor like rancid cheese; [Merck Index] Clear colorless liquid with a disagreeable odor; [CHEMINFO]

Sources/Uses

Found in hop oil, tobacco, and other plants; [Merck Index] Used as a fragrance and flavor and to make fungicides, rodenticides, sedatives, narcotics, and other drugs; [HSDB] Used to make esters for solvents, softeners, and perfumes; [CHEMINFO]

Comments

Safe when used as a flavoring agent in food; [JECFA] Mild irritant when administered to eye of rabbit; Corrosive to skin of mice; Caused somnolence and ataxia in lethal-dose feeding studies of rats; [RTECS] Corrosive to tissue; [CAMEO] A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; [CHEMINFO] A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; Inhalation may cause chemical pneumonitis and pulmonary edema; [MSDSonline]

Exposure Assessment
Vapor Pressure

0.44 mm Hg

Odor Threshold Low

0.0015 ppm

Odor Threshold High

0.72 ppm

Explanatory Notes

Odor threshold from CHEMINFO;

Adverse Effects
Toxic Pneumonitis

Yes

Neurotoxin

Other CNS Neurotoxin

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Related Information in HazMap
Other Information

No other related information on this agent was found.