Agent Name

Octachloronaphthalene

CAS Number

2234-13-1

Formula

C10-Cl8

Major Category

Other Classes

Synonyms

1,2,3,4,5,6,7,8-Octachloronaphthalene; Halowax 1051; Naphthalene, octachloro-; Octachloro naphthalene; Octachloronaphthalene; Perchloronaphthalene; Perna; [ChemIDplus]

Category

Halowaxes

Description

Waxy, pale-yellow solid with an aromatic odor; [NIOSH]

Sources/Uses

Used as additives to lubricants and cable insulation (fire retardants); [ACGIH]

Comments

Chlorinated naphthalenes may be absorbed through the skin. They cause liver injury and hyperkeratosis in experimental animals. Penta- and hexachloronaphthalene may cause in exposed workers acne-like lesions that itch severely. Tri-, tetra-, and octachloronaphthalene are non-acnegenic under the conditions of industrial use. Nine occupational fatalities from chlorinated naphthalene poisoning have been reported. Most cases of intoxication among cable workers, assemblers, and laborers involve either penta- or hexachloronaphthalene. A nonfatal case of toxic hepatitis was reported in an 18 year old female who was soldering electrical condensers. [ACGIH] Acne-form dermatitis is listed as an adverse effect for all of the halowaxes except trichloronaphthalene in the NIOSH Pocket Guide. "Overexposure to octachloronaphthalene may cause an acne like skin rash. It may also injure the liver, resulting in such effects as fatigue, dark urine, yellow jaundice, and possibly death." [NIOSH Guidelines for Chemical Hazards]

Reference Link

CHLORINATED NAPHTHALENES (CICAD 34, 2001)

Exposure Assessment
Skin Designation (ACGIH)

Yes

Bioaccumulates

Yes

TLV (ACGIH)

0.1 mg/m3

STEL (ACGIH)

0.3 mg/m3

PEL (OSHA)

0.1 mg/m3

Excerpts from Documentation for IDLHs

Basis for original (SCP) IDLH: AIHA [1966] reported that the atmospheric concentration immediately hazardous to life is probably unattainable for the chloronaphthalenes with the possible exception of monochloronaphthalene. . . . Basis for revised IDLH: Due to a lack of relevant acute toxicity data, the IDLH for octachloronaphthalene remains "Unknown."

Vapor Pressure

1.1E-8 mm Hg

Explanatory Notes

flash point > 430 deg C;

Adverse Effects
Hepatotoxin

Hepatotoxin, Primary

Dermatotoxin

Chloracne

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: