Agent Name

Licorice extract

CAS Number

68916-91-6

Major Category

Biological Agents

Synonyms

Glycyrrhiza extract; Glycyrrhizae [Latin]; Kanzo [Japanese]; Kanzou [Chinese]; Licorice extract (Glycyrrhiza spp.); Licorice extract powder (Glycyrrhiza glabra L.); Licorice root (Glycyrrhiza glabra L.); Licorice root extract; [ChemIDplus]

Category

Plant Oils and Extracts

Description

Liquid or dried extract; [HSDB] Light yellow to brownish-yellow powder with a sweet spicy odor; [MSDSonline]

Sources/Uses

From rhizome and root of Glycyrrhiza glabra; Used for flavoring confectionery and pharmaceutical products, as a humectant in tobacco, and in herbal remedies and modern drugs; [HSDB]

Comments

Emergency treatment: "Liquorice"; "Hypokalemia, hypernatremia, and water retention are primary problems associated with chronic liquorice ingestion." [HSDB] Glycyrrhizin is the major active compound (triterpene glycoside) in licorice root. It has been used as an herbal remedy for ulcers, inflammation, and viral infections. After ingestion and hydrolysis, the compound inhibits an enzyme that results in increased serum cortisol levels. [Haddad, p. 485] May cause eye irritation; Repeated or prolonged ingestion may cause hypokalemia and injury to liver and kidneys; [Science Lab MSDS] See "Glycyrrhizin."

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

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