Agent Name

Linalool

Alternative Name

Linalyl alcohol

CAS Number

78-70-6

Formula

C10-H18-O

Major Category

Biological Agents

Synonyms

Linalyl alcohol; (+-)-Linalool; 1,6-Octadien-3-ol, 3,7-dimethyl-; 2,6-Dimethyl-2,7-octadiene-6-ol; 2,6-Dimethylocta-2,7-dien-6-ol; 3,7-Dimethyl-1,6-octadien-3-ol; 3,7-Dimethylocta-1,6-dien-3-ol; Linalool (natural); allo-Ocimenol; beta-Linalool; p-Linalool; [ChemIDplus]

Category

Plant Oils and Extracts

Description

Colorless liquid with an odor of bergamot oil or French lavender; [Hawley]

Sources/Uses

Main component of linaloe oil; Also found in oils of Ceylon cinnamon, sassafras, orange flower, and bergamot; [Merck Index] Found in citrus peel oils (especially orange); [Hawley] Used in perfumes, fragrances, flavoring agents, household cleaners, and insecticidal pet treatments; (direct application to pet and indoor area); [HSDB]

Comments

A skin and eye irritant; May cause liver injury; [ICSC] Emergency treatment: "Linalool"; A skin and eye irritant; [HSDB] Safe to use as a flavoring agent in food; [JECFA] Slight sedative effects after inhalation; Not a sensitizer; Not mutagenic; Causes effects on liver and kidneys in 28-day rat feeding study (72.9% linalool) with a NOAEL of 160 mg/kg/day; [Reference #1] Included in list of "established contact allergens in humans"; [ToxPlanet: EC: Scientific Committee on Consumer Safety: Fragrance allergens in cosmetic products (2011)]

Reference Link

OECD SIDS: Linalool - 2002

Exposure Assessment
Vapor Pressure

0.16 mm Hg

Odor Threshold Low

1 ppm

Explanatory Notes

Olfactory threshold is approximately 1 ppm; [Reference #1]

Flammability (NFPA)

2: High ambient temperature required

Adverse Effects
Skin Sensitizer

Yes

Neurotoxin

CNS Solvent Syndrome

Hepatotoxin

Hepatotoxin, Secondary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: