Agent Name

Pentachloronaphthalene

CAS Number

1321-64-8

Formula

C10-H3-Cl5

Major Category

Other Classes

Synonyms

Halowax 1013; [NIOSH]

Category

Halowaxes

Description

Pale-yellow or white solid or powder with an aromatic odor; [NIOSH]

Sources/Uses

Used as additives to lubricants and cable insulation (fire retardants); [ACGIH]

Comments

Chlorinated naphthalenes may be absorbed through the skin. They cause liver injury and hyperkeratosis in experimental animals. Penta- and hexachloronaphthalene may cause in exposed workers acne-like lesions that itch severely. Tri-, tetra-, and octachloronaphthalene are non-acnegenic under the conditions of industrial use. Nine occupational fatalities from chlorinated naphthalene poisoning have been reported. Most cases of intoxication among cable workers, assemblers, and laborers involve either penta- or hexachloronaphthalene. A nonfatal case of toxic hepatitis was reported in an 18 year old female who was soldering electrical condensers. [ACGIH] Acne-form dermatitis is listed as an adverse effect for all of the halowaxes except trichloronaphthalene in the NIOSH Pocket Guide. A skin and eye irritant; [ICSC]

Reference Link

CHLORINATED NAPHTHALENES (CICAD 34, 2001)

Exposure Assessment
Skin Designation (ACGIH)

Yes

Bioaccumulates

Yes

TLV (ACGIH)

0.5 mg/m3

PEL (OSHA)

0.5 mg/m3

Excerpts from Documentation for IDLHs

Basis for original (SCP) IDLH: AIHA [1970] reported that the atmospheric concentration immediately hazardous to life is probably unattainable for the chloronaphthalenes with the possible exception of monochloronaphthalene. . . . Basis for revised IDLH: Due to a lack of relevant acute toxicity data, the IDLH for pentachloronaphthalene remains "Unknown."

Vapor Pressure

1.49E-5 mm Hg

Explanatory Notes

See "2018 Notice of Intended Changes." [TLVs and BEIs]

Adverse Effects
Hepatotoxin

Hepatotoxin, Primary

Dermatotoxin

Chloracne

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: