Agent Name

Ethyl chloride

Alternative Name

Chloroethane

CAS Number

75-00-3

Formula

C2-H5-Cl

Major Category

Solvents

Synonyms

Aethylchlorid [German]; Aethylchloride [German]; Aethylis chloridum; Anodynon; Chelen; Chloorethaan [Dutch]; Chlorene; Chlorethyl; Chloroaethan [German]; Chloroethane; Chlorure d'ethyle [French]; Chloryl; Chloryl anesthetic; Cloretilo; Cloroetano [Italian]; Cloruro di etile [Italian]; Dublofix; Ethane, chloro-; Ether chloratus; Ether chloridum; Ether hydrochloric; Ether muriatic; Ethyl chloride; Etylu chlorek [Polish]; Hydrochloric ether; Kelene; Monochlorethane; Monochloroethane; Muriatic ether; Narcotile; [ChemIDplus] UN1037

Category

Chlorinated Aliphatics

Description

Colorless gas or liquid (below 54 degrees F) with a pungent, ether-like odor; Note: Shipped as a liquefied compressed gas; [NIOSH]

Sources/Uses

Used as an intermediate in organic synthesis, a solvent, an alkylating agent, a propellant in aerosols, and an anesthetic; [ACGIH]

Comments

Liver injury has been documented in studies of experimental animals. [ACGIH] Ethyl chloride is in the list of "Some volatile substances which may be abused by inhalation" published on the web site of the U.N. International Drug Control Programme, indicating its potential to cause narcosis in workers. [Reference #1]

Reference Link

Volatile Substance Abuse

Exposure Assessment
Skin Designation (ACGIH)

Yes

TLV (ACGIH)

100 ppm

PEL (OSHA)

1000 ppm

IDLH (NIOSH)

3800 ppm

Excerpts from Documentation for IDLHs

Human data: It has been reported that 13,000 ppm for 21 minutes caused no difficulty in walking or balancing but 19,000 ppm caused weak analgesia and slight dizziness after 12 minutes [Davidson 1926].

Vapor Pressure

1000 mm Hg

Odor Threshold Low

4.2 ppm

Lethal Concentration

LC50 (rat) = 152,000 mg/m3/2H

Explanatory Notes

IDLH = 10% LEL (lower explosive limit); Odor threshold from NJ "Hazardous Substance Fact Sheet"; Flash point = -50 deg C;

Reference Link

ATSDR - ToxFAQs - Chloroethane

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Hepatotoxin

Hepatotoxin, Secondary

IARC Carcinogen

Not Classifiable

ACGIH Carcinogen

Confirmed Animal

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

Search ChemIDplus

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: