Agent Name

Phenyl ether, vapor

Alternative Name

Diphenyl ether

CAS Number

101-84-8

Formula

C12-H10-O

Major Category

Other Classes

Synonyms

1,1'-Oxybis(benzene); Benzene, 1,1'-oxybis-; Benzene, phenoxy-; Biphenyl oxide; Chemcryl JK-EB; Diphenyl ether; Diphenyl oxide; Ether, diphenyl-; Geranium crystals; Oxybisbenzene; Oxydiphenyl; Phenoxybenzene; Phenyl oxide; [ChemIDplus] UN3077

Category

Other Aromatic Compounds

Description

Colorless, crystalline solid or liquid (above 82 degrees F) with a geranium-like odor; [NIOSH]

Sources/Uses

Used as a heat transfer medium, Dowtherm A, and as a chemical intermediate for surface active agents and lubricants; [ACGIH]

Comments

Damage to the liver and other organs has been documented in acute studies of experimental animals; [ACGIH] An irritant of the eyes and respiratory tract; [ICSC]

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TLV (ACGIH)

1 ppm

STEL (ACGIH)

2 ppm

PEL (OSHA)

1 ppm

MAK

1 ppm

IDLH (NIOSH)

100 ppm

Excerpts from Documentation for IDLHs

Other animal data: Rats exposed to 20 ppm for 7 hours per day for 20 days exhibited only eye and nasal irritation [Hefner et al. 1975]. Human data: It has been reported that industrial experience has shown no evidence that phenyl ether, either as a liquid, mist, or vapor, is a health hazard under ordinary conditions of production and use; no overt systemic toxicity was found at concentrations that were not intolerably disagreeable [Clayton and Clayton 1981].

Vapor Pressure

0.02 mm Hg

Odor Threshold Low

0.1 ppm

Explanatory Notes

Odor threshold (recognition) from CHEMINFO; Flash point = 115 deg C;

Flammability (NFPA)

1: Must be preheated

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Chemical Information

Search ChemIDplus

Related Information in HazMap
Other Information

No other related information on this agent was found.