Agent Name

Phenylphosphine

CAS Number

638-21-1

Formula

C6-H7-P

Major Category

Other Classes

Synonyms

Fenylfosfin; PF; Phosphaniline; [NIOSH]

Category

Phosphorus Compounds

Description

Clear, colorless liquid with a foul odor; [NIOSH]

Sources/Uses

Used as chemical intermediates; produced when phenylphosphinates are heated above 200 degrees C. [ACGIH]

Comments

A respiratory irritant with a repulsive odor; Phenylphosphine causes anemia and severe testicular degeneration in rats inhaling 2.2 ppm for 90 days. The acute toxicity of inhaled phenylphosphine is about 1/4 that of phosphine. Animals exposed to 2.2 ppm for 4 weeks have reversible hemolytic anemia. [ACGIH] A skin, eye, and respiratory tract irritant; [ICSC]

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

Ceiling (ACGIH)

0.05 ppm

Vapor Pressure

2.45 mm Hg

Lethal Concentration

LC50 (rat) = 38 ppm/4h

Adverse Effects
Anemia

Anemia, Hemolytic

Reproductive Toxin

Yes

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Related Information in HazMap
Other Information

No other related information on this agent was found.