Agent Name

Mephosfolan

CAS Number

950-10-7

Formula

C8-H16-N-O3-P-S2

Major Category

Pesticides

Synonyms

(4-Methyl-1,3-dithiolan-2-ylid-ene)phosphoramidic acid diethyl ester; (Diethoxyphosphinyl)dithioimidocarbonic acid cyclic propylene ester; 1,2-Propanedithiol, cyclic ester with P,P-diethyl phosphonodithioimidocarbonate; 2-(Diethoxyphosphinylimino)-4-methyl-1,3-dithiolane; AC 47470; American Cyanamid CL-47470; CL-47,470; Cyclic propylene (diethoxyphosphinyl)dithioimidocarbonate; Cyclic propylene P,P-diethyl phosphonodithioimidocarbonate (8CI); Cytrolane; Cytrolane insecticide; Diethyl (4-methyl-1,3-dithiolan-2-ylidene)phosphoroamidate; EI-47470; ENT-25,991; Imidocarbonic acid, phosphonodithio-, cyclic propylene P,P-diethyl ester; Mephospholan [ISO-French]; O,O-Diethyl(4-methyl-1,3-dithiolan-2-ylidene)phosphoramidate; P,P-Diethyl cyclic propylene ester of phosphonodithioimidocarbonic acid; Phosphonodithioimidocarbonic acid cyclic propylene P,P-diethyl ester; Phosphoramidic acid, (4-methyl-1,3-dithiolan-2-ylidene)-, diethyl ester; [ChemIDplus]

Category

Organophosphate Insecticides

Description

Colorless or yellow to amber liquid; [HSDB]

Sources/Uses

Used as contact and stomach insecticide and acaricide for cotton, fruits, vegetables, maize, and other crops; [HSDB]

Comments

A highly toxic cholinesterase inhibitor; [CAMEO] The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline. [TLVs and BEIs]

Restricted

Not registered in the US for use as pesticide; [CAMEO]

Exposure Assessment
BEI

Acetylcholinesterase activity in red blood cells = 70% of individual's baseline; Butylcholinesterase activity in serum or plasma = 60% of individual's baseline; Sample at end of shift; [TLVs and BEIs]

Vapor Pressure

3.18E-5 mm Hg

Adverse Effects
Other Poison

Organophosphate

Links to Other NLM Databases
Health Studies

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Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: